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Gene Expression Data
Assay Details
Assay
Reference: J:157819 Shimogori T, et al., A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
Assay type: RNA in situ
MGI Accession ID: MGI:4450749
Gene symbol: Fgf15
Gene name: fibroblast growth factor 15
Probe: Fgf15 EST
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S8a: embryonic day 11.5 (more )
Note: Double labeled: blue - Fgf15; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S8_a Expression is present in a dorsal domain that encompasses the eminentia thalami, prethalamus and the paraventricular hypothalamic nucleus.
Specimen S8b: embryonic day 11.5 (more )
Note: Double labeled: blue - Fgf15; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S8_b Expression is present in a dorsal domain that encompasses the eminentia thalami, prethalamus and the paraventricular hypothalamic nucleus.
Specimen S8c: embryonic day 11.5 (more )
Note: Double labeled: blue - Fgf15; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S8_c Expression is present in a dorsal domain that encompasses the eminentia thalami, prethalamus and the paraventricular hypothalamic nucleus.
Specimen S8d: embryonic day 11.5 (more )
Note: Double labeled: blue - Fgf15; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted S8_d Expression is present in a dorsal domain that encompasses the eminentia thalami, prethalamus and the paraventricular hypothalamic nucleus.
Specimen Fgf15 - E11.5: embryonic day 11.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS19: diencephalon lateral wall mantle layer Ambiguous Fgf15-Shh E11.5-sagittal , Fgf15-Shh E11.5-sagittal-2 , Fgf15-Shh E11.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
TS19: diencephalon lateral wall ventricular layer Very strong Non-Uniform Fgf15-Shh E11.5-sagittal , Fgf15-Shh E11.5-sagittal-2 , Fgf15-Shh E11.5-coronal There is very strong staining in the VZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs & the AVH. Staining is either absent or ubiquitous in the VZ of PVH, VMH & ARH nuclei, anterior & posterior IDs, the premam, mam & supramam zones & the TT.
TS19: telencephalon mantle layer Ambiguous Fgf15-Shh E11.5-coronal , Fgf15-Shh E11.5-sagittal , Fgf15-Shh E11.5-sagittal-2 Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
TS19: telencephalon ventricular layer Very strong Non-Uniform Fgf15-Shh E11.5-sagittal-2 , Fgf15-Shh E11.5-sagittal , Fgf15-Shh E11.5-coronal There is very strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Fgf15 - E12.5: embryonic day 12.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS20: cerebral cortex intermediate zone Ambiguous Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal-2 Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS20: cerebral cortex ventricular layer Ambiguous Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-sagittal-2 , Fgf15-Shh E12.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS20: cortical plate Ambiguous Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal-2 , Fgf15-Shh E12.5-sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS20: diencephalon mantle layer Ambiguous Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-sagittal-2 Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
TS20: diencephalon ventricular layer Ambiguous Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal-2 , Fgf15-Shh E12.5-sagittal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS20: ganglionic eminence Very strong Non-Uniform Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal-2 There is very strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
TS20: hypothalamus mantle layer Ambiguous Fgf15-Shh E12.5-sagittal-2 , Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS20: hypothalamus ventricular layer Very strong Non-Uniform Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal-2 There is very strong staining in the ventricular zone of the dorsal and ventral POAs and the AVH. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei and anterior and posterior IDs.
TS20: thalamus mantle layer Ambiguous Fgf15-Shh E12.5-sagittal-2 , Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS20: thalamus ventricular layer Very strong Fgf15-Shh E12.5-coronal , Fgf15-Shh E12.5-sagittal , Fgf15-Shh E12.5-sagittal-2 There is very strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Fgf15 - E14.5: embryonic day 14.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Ambiguous Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-coronal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS22: cerebral cortex ventricular layer Ambiguous Fgf15-Shh E14.5-coronal , Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS22: cortical plate Ambiguous Fgf15-Shh E14.5-coronal , Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS22: diencephalon mantle layer Strong Non-Uniform Fgf15-Shh E14.5-coronal , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-sagittal-2 There is strong staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones and the TT.
TS22: diencephalon ventricular layer Ambiguous Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS22: ganglionic eminence Very strong Non-Uniform Fgf15-Shh E14.5-coronal , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-sagittal-2 There is very strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
TS22: hypothalamus mantle layer Ambiguous Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS22: hypothalamus ventricular layer Very strong Non-Uniform Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-coronal , Fgf15-Shh E14.5-sagittal There is very strong staining in the ventricular zone of the dorsal and ventral POA and the AVH. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei and anterior and posterior IDs.
TS22: thalamus mantle layer Ambiguous Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS22: thalamus ventricular layer Very strong Fgf15-Shh E14.5-sagittal-2 , Fgf15-Shh E14.5-sagittal , Fgf15-Shh E14.5-coronal There is very strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Fgf15 - E16.5: embryonic day 16.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Ambiguous Fgf15-Shh E16.5-sagittal-2 , Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS24: cerebral cortex ventricular layer Ambiguous Fgf15-Shh E16.5-sagittal-2 , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS24: cortical plate Ambiguous Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 , Fgf15-Shh E16.5-coronal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS24: diencephalon mantle layer Strong Non-Uniform Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 There is strong staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones.
TS24: diencephalon ventricular layer Ambiguous Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
TS24: ganglionic eminence Strong Non-Uniform Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 There is strong staining in the ventricular zone of the ganglionic eminences and moderate, scattered staining in the mantle zone of the ganglionic eminences.
TS24: hypothalamus mantle layer Ambiguous Fgf15-Shh E16.5-sagittal-2 , Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
TS24: hypothalamus ventricular layer Ambiguous Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
TS24: thalamus mantle layer Ambiguous Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS24: thalamus ventricular layer Very strong Fgf15-Shh E16.5-coronal , Fgf15-Shh E16.5-sagittal , Fgf15-Shh E16.5-sagittal-2 There is very strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
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11/19/2024
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