Mdktm1(KOMP)Mbp
Targeted Allele Detail
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| Symbol: |
Mdktm1(KOMP)Mbp |
| Name: |
midkine; targeted mutation 1, Mouse Biology Program, UC Davis |
| MGI ID: |
MGI:4454006 |
| Gene: |
Mdk Location: Chr2:91760149-91762348 bp, - strand Genetic Position: Chr2, 50.63 cM
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| Alliance: |
Mdktm1(KOMP)Mbp page
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| IMPC: |
Mdk gene page |
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| Mutant Cell Lines: |
DEPD00513_1_A09, DEPD00513_1_A10, DEPD00513_1_B09, DEPD00513_1_C09, DEPD00513_1_C11, DEPD00513_1_C12, DEPD00513_1_D09, DEPD00513_1_D10, DEPD00513_1_D12, DEPD00513_1_E09, DEPD00513_1_E10, DEPD00513_1_G09, DEPD00513_1_G10, DEPD00513_1_G11, DEPD00513_1_H10 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Project Collection: |
KOMP-CSD
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 697 starting at position 91761104 and ending at position 91761801 of Chromosome 2 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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| Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
| All: |
2 reference(s) |
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Analysis Tools
