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Gene Expression Data
Assay Details
Assay
Reference: J:152838 Fu H, et al., A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4839597
Gene symbol: Tcf7l2
Gene name: transcription factor 7 like 2, T cell specific, HMG box
Results
Specimen 5 - E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord Weak Single cells 5_E18.5 There is barely detectable expression within a minor subset of cells in the ventral spinal cord.
Specimen 5 - P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal cord Present Single cells 5_P0 Expression cells are dispersed throughout the gray and white matter.
Specimen 5 - P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells 5_P5 Expression cells are dispersed throughout the gray and white matter.
Specimen 5 - P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells 5_P14 Expression cells are dispersed throughout the gray and white matter.
Specimen 5 - Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord white matter Absent 5_Adult
Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: corpus callosum Absent
Specimen 6C - P0: postnatal day 0 (more )
Note: Double labeled: red - Tcf7l2; green - Mki67 (assay MGI:4839608).
Structure Level Pattern Image Note
TS27: spinal cord Present Single cells 6C P0 Expression is present in post-mitotic oligodendrocytes; it is not present in dividing cells.
Specimen 6C - P5: postnatal day 5 (more )
Note: Double labeled: red - Tcf7l2; green - Mki67 (assay MGI:4839608).
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells 6C P5 Expression is present in post-mitotic oligodendrocytes; it is not present in dividing cells.
Specimen 6C - P10: postnatal day 14 (more )
Note: Double labeled: red - Tcf7l2; green - Mki67 (assay MGI:4839608).
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells 6C P14 Expression is present in post-mitotic oligodendrocytes; it is not present in dividing cells.
Specimen S1A: embryonic day 18.5 (more )
Note: Double labeled: red - Tcf7l2; green - Olig2 (assay MGI:4839209).
Structure Level Pattern Image Note
TS26: spinal cord Present Single cells S1_A Expression is present in oligodendrocyte lineage cells.
Specimen S1B: postnatal day 0 (more )
Note: Double labeled: red - Tcf7l2; green - Olig2 (assay MGI:4839209).
Structure Level Pattern Image Note
TS27: spinal cord Present Single cells S1_B Expression is present in oligodendrocyte lineage cells; its level decreases as myelination proceeds.
Specimen S1C: postnatal day 5 (more )
Note: Double labeled: red - Tcf7l2; green - Olig2 (assay MGI:4839209).
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells S1_C Expression is present in oligodendrocyte lineage cells; its level decreases as myelination proceeds.
Specimen S1D: postnatal day 14 (more )
Note: Double labeled: red - Tcf7l2; green - Olig2 (assay MGI:4839209).
Structure Level Pattern Image Note
TS28: spinal cord Present Single cells S1_D Expression is present in oligodendrocyte lineage cells; its level decreases as myelination proceeds.
Specimen 8: postnatal day 5 (more )
Note: Double labeled: red - Tcf7l2; green - Ctnnb1 (assay MGI:4839636).
Structure Level Pattern Image Note
TS28: spinal cord white matter Present Single cells 8_B Tcf4 , 8_B Tcf4/B-Catenin
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory