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Gon7 Gene Detail
Summary
  • Symbol
    Gon7
  • Name
    GON7 subunit of KEOPS complex
  • Synonyms
    AK010878
  • Feature Type
    protein coding gene
  • IDs
    MGI:4845848
    NCBI Gene: 100233175
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:102719534-102724062 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 52.14 cM
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4845848
 protein coding gene Chr12:102719534-102724069 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020039
 protein coding gene Chr12:104411072-104416318 (-)
A/J MGP_AJ_G0019995
 protein coding gene Chr12:100392659-100397187 (-)
AKR/J MGP_AKRJ_G0019971
 protein coding gene Chr12:103234410-103238939 (-)
BALB/cJ MGP_BALBcJ_G0019981
 protein coding gene Chr12:100744713-100749544 (-)
C3H/HeJ MGP_C3HHeJ_G0019783
 protein coding gene Chr12:103708775-103713303 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020430
 protein coding gene Chr12:107648105-107654962 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018043
 protein coding gene Chr12:97405213-97409120 (-)
CAST/EiJ MGP_CASTEiJ_G0019329
 protein coding gene Chr12:98552208-98556543 (-)
CBA/J MGP_CBAJ_G0019755
 protein coding gene Chr12:111651778-111658854 (-)
DBA/2J MGP_DBA2J_G0019866
 protein coding gene Chr12:99910771-99915096 (-)
FVB/NJ MGP_FVBNJ_G0019855
 protein coding gene Chr12:98642723-98647189 (-)
LP/J MGP_LPJ_G0019942
 protein coding gene Chr12:104251595-104256036 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019895
 protein coding gene Chr12:115109928-115116553 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020459
 protein coding gene Chr12:102748079-102753363 (-)
PWK/PhJ MGP_PWKPhJ_G0019092
 protein coding gene Chr12:94469097-94473490 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018888
 protein coding gene Chr12:96948491-96954602 (-)
WSB/EiJ MGP_WSBEiJ_G0019383
 protein coding gene Chr12:103642382-103647872 (-)



Homology
more
  • Human Ortholog
    GON7, GON7 subunit of KEOPS complex
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GON7, GON7 subunit of KEOPS complex
  • Synonyms
    C14orf142, PNAS-127
  • Links
    NCBI Gene ID: 84520
    neXtProt AC: NX_Q9BXV9
    UniProt: Q9BXV9

  • Chr Location
    14q32.12; chr14:93202894-93207065 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human GON7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091931 Ensembl Gene Model | MGI Sequence Detail 4529 C57BL/6J ±  kb
transcript ENSMUST00000173969 Ensembl | MGI Sequence Detail 1152 Not Applicable  
polypeptide ENSMUSP00000136425 Ensembl | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR027893 EKC/KEOPS complex subunit GON7, metazoa
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 13
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
  • Latest
    J:342605 GOA curators, Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. 2016;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory