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Arrb2tm1.1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Arrb2tm1.1(KOMP)Vlcg
Name: arrestin, beta 2; targeted mutation 1.1, Velocigene
MGI ID: MGI:5445919
Gene: Arrb2  Location: Chr11:70323461-70331654 bp, + strand  Genetic Position: Chr11, 42.99 cM
Alliance: Arrb2tm1.1(KOMP)Vlcg page
IMPC: Arrb2 gene page
Mutation
origin
Mutant Cell Line:  17027A-F6
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7625bp between positions 70246236-70253860 of Chromosome 11 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 48 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arrb2 Mutation:  27 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory