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Gene Expression Data
Assay Details
Assay
Reference: J:86704 Maynard TM, et al., A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14433-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5588018
Gene symbol: Comt
Gene name: catechol-O-methyltransferase
Antibody: COMT antibody
Detection system: fluorescein
Assay notes: Specimens were fixed in 2.5% paraformaldehyde.
Results
Specimen 2d: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex marginal layer Present 2d
TS24: cortical plate Present 2d
Specimen 2e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 2e Expression in subsets of neurons in multiple neocortical layers.
Specimen 4 cerebellum: postnatal adult (more )
Note: Double labeled: green - Comt; red - Calb1 (assay MGI:5588111).
Structure Level Pattern Image Note
TS28: cerebellum Present Regionally restricted 4_COMT Cerebellum Neuronal expression.
Specimen 4 hippocampus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA4 Present 4_COMT Hippocampus
Specimen 4 dentate gyrus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 4_COMT Dentate Gyrus
Specimen 4 striatum: postnatal adult (more )
Structure Level Pattern Image Note
TS28: basal ganglia Present Regionally restricted 4_COMT Striatum Expression in subsets of basal ganglia neurons.
TS28: corpus striatum Present 4_COMT Striatum
Specimen 6 cortex: postnatal adult (more )
Note: Double labeled: green - Comt; red - Septin5 (assay MGI:3028312).
Structure Level Pattern Image Note
TS28: cerebral cortex Present 6_COMT + CDCrel-1 Cortex
Specimen 6 striatum: postnatal adult (more )
Note: Double labeled: green - Comt; red - Septin5 (assay MGI:3028312).
Structure Level Pattern Image Note
TS28: corpus striatum Present 6_COMT + CDCrel-1 Striatum
Specimen 6 hippocampus: postnatal adult (more )
Note: Double labeled: green - Comt; red - Septin5 (assay MGI:3028312).
Structure Level Pattern Image Note
TS28: hippocampus Present 6_COMT + CDCrel-1 Hippocampus
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted Neuronal expression.
TS28: thalamus Present Regionally restricted Neuronal expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory