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Gene Expression Data
Assay Details
Assay
Reference: J:162095 Shiwaku H, et al., Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010 Jul 21;29(14):2446-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5638221
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: Anti-Calbindin
Detection system: Secondary antibody
Results
Specimen 6A WT 1w: postnatal week 1 (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A WT Merge 1w , 6A WT Calbindin 1w
Specimen 6A Atx1-KI 1w: postnatal week 1; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A Atx1-KI Calbindin 1w , 6A Atx1-KI Merge 1w
Specimen 6A WT 16w: postnatal week 16 (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A WT Calbindin 16w , 6A WT Merge 16w
Specimen 6A Atx1-KI 16w: postnatal week 16; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A Atx1-KI Merge 16w , 6A Atx1-KI Calbindin 16w
Specimen 6A WT 40w: postnatal week 40 (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A WT Calbindin 40w , 6A WT Merge 40w
Specimen 6A Atx1-KI 40w: postnatal week 40; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox2 (assay MGI:5638219).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6A Atx1-KI Merge 40w , 6A Atx1-KI Calbindin 40w Purkinje cell reduction in the mutant started at 19 weeks.
Specimen S1A: postnatal week 16 (more )
Note: Double labeled: red - Calb1; green - Ufl1 (assay MGI:5638165).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S1A Calbindin , S1A Merge
Specimen S5A WT 1w: postnatal week 1 (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A WT Calbindin 1w , S5A WT Merge 1w
Specimen S5A Atx1-KI 1w: postnatal week 1; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A Atx1-KI Merge 1w , S5A Atx1-KI Calbindin 1w
Specimen S5A WT 16w: postnatal week 16 (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A WT Calbindin 16w , S5A WT Merge 16w
Specimen S5A Atx1-KI 16w: postnatal week 16; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A Atx1-KI Merge 16w , S5A Atx1-KI Calbindin 16w
Specimen S5A WT 40w: postnatal week 40 (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A WT Calbindin 40w , S5A WT Merge 40w
Specimen S5A Atx1-KI 40w: postnatal week 40; Atxn1tm1Hzo/Atxn1+ (more )
Note: Double labeled: red - Calb1; green - Sox9 (assay MGI:5638224).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present S5A Atx1-KI Merge 40w , S5A Atx1-KI Calbindin 40w Purkinje cell reduction in the mutant started at 19 weeks.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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