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Gene Expression Data
Assay Details
Assay
Reference: J:215153 Follit JA, et al., Arf4 is required for Mammalian development but dispensable for ciliary assembly. PLoS Genet. 2014 Feb;10(2):e1004170
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5695248
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Results
Specimen 6E +/+: embryonic day 8.5 (more )
Note: Double labeled: green - Lrp2; red - Golgb1 (assay MGI:5695251).
Structure Level Pattern Image Note
TS13: embryo endoderm Present Regionally restricted 6E +/+ Merge , 6E +/+ Megalin Expression was detected along the apical surface of the visceral endoderm.

Specimen 6E -/-: embryonic day 8.5; Arf4Gt(AY0614)Wtsi/Arf4Gt(AY0614)Wtsi (more )
Note: Double labeled: green - Lrp2; red - Golgb1 (assay MGI:5695251).
Structure Level Pattern Image Note
TS13: embryo endoderm Weak Regionally restricted 6E -/- Megalin , 6E -/- Merge Mutants have significantly reduced staining at the apical surface and some of the protein appears in the cytoplasm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory