Nrp2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:176047 Fantin A, et al., The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins. Development. 2011 Oct;138(19):4185-91
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5752538
Gene symbol:	Nrp2
Gene name:	neuropilin 2

Antibody:	anti-Nrp2
Detection system:	Secondary antibody coupled to fluorescein

Results

4A ©

Specimen 4A: postnatal day 21 (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel	Present		4A

S2_A ©

Specimen S2A: postnatal day 7 (more

)
Note: Double labeled: red - Nrp2; green - Cspg4 (assay MGI:5752539).

Structure	Level	Pattern	Image	Note
TS28: retina blood vessel	Present	Non-Uniform	S2_A , S2_NRP2 upper	Expression levels are higher on veins than arteries.
TS28: neural retina	Present	Regionally restricted	S2_A , S2_NRP2 upper	Expressed in axons underneath the vessel plexus.

S2_B ©

Specimen S2B: postnatal day 7; Nrp1^tm1.1Cruh/Nrp1^tm1.1Cruh (more

)
Note: Double labeled: red - Nrp2; green - Cspg4 (assay MGI:5752539).

Structure	Level	Pattern	Image	Note
TS28: retina blood vessel	Present	Non-Uniform	S2_B , S2_NRP2 lower	Expression levels are higher on veins than arteries, same as in the wild-type.
TS28: neural retina	Present	Regionally restricted	S2_B , S2_NRP2 lower	Expressed in axons underneath the vessel plexus, same as in the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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