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Gene Expression Data
Assay Details
Assay
Reference: J:237110 Lee YG, et al., Coordinated lymphangiogenesis is critical in lymph node development and maturation. Dev Dyn. 2016 Dec;245(12):1189-1197
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197056
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: Anti-Lyve1
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 3B P1: postnatal day 1 (more )
Note: Triple labeled: green - Lyve1; blue - Pecam1 (assay MGI:6197053); red - Cd4 (assay MGI:6197052).
Structure Level Pattern Image Note
TS27: lymph node Present Regionally restricted 3B P1 Expression was detected in macrophages. Labeled cells were in a separate population of cells than the CD4-immunopositive T cells.
TS27: lymphatic vessel Present 3B P1

Specimen 3B P2: postnatal day 2 (more )
Note: Triple labeled: green - Lyve1; blue - Pecam1 (assay MGI:6197053); red - Cd4 (assay MGI:6197052).
Structure Level Pattern Image Note
TS27: lymph node Present Regionally restricted 3B P2 Expression was detected in macrophages. Labeled cells were in a separate population of cells than the CD4-immunopositive T cells.
TS27: lymphatic vessel Present 3B P2

Specimen 3D P3 +/+: postnatal day 3 (more )
Note: Triple labeled: green - Lyve1; blue - Pecam1 (assay MGI:6197053); red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS27: lymph node Present 3D Vegfc+/+
TS27: lymphatic vessel Present 3D Vegfc+/+

Specimen 3D P3 +/LacZ: postnatal day 3; Vegfctm1Ali/Vegfc+ (more )
Note: Triple labeled: green - Lyve1; blue - Pecam1 (assay MGI:6197053); red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS27: lymphatic vessel Present 3D Vegfc+/LacZ

Specimen 4O: postnatal day 7 (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymph node Present 4O' , 4O
TS28: lymphatic vessel Present 4O' , 4O

Specimen 4P: postnatal day 7; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymphatic vessel Present 4P , 4P'

Specimen 4Q: postnatal day 14 (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymph node Present 4Q , 4Q'
TS28: lymphatic vessel Present 4Q , 4Q'

Specimen 4R: postnatal day 14; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymphatic vessel Present 4R' , 4R

Specimen 4S: postnatal adult (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymph node Present 4S , 4S'
TS28: lymphatic vessel Present 4S , 4S'

Specimen 4T: postnatal adult; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Lyve1; red - Ptprc (assay MGI:6197072).
Structure Level Pattern Image Note
TS28: lymphatic vessel Present 4T' , 4T


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory