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Gene Expression Data
Assay Details
Assay
Reference: J:229950 Fujita M, et al., Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor. Mech Dev. 2016 Feb;139:65-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6236305
Gene symbol: Tagln
Gene name: transgelin
Results
Specimen 3a: embryonic day 10.5 (more )
Note: Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS17: 4th arch artery Present Regionally restricted 3a , 3a' , 3a''' Expression was detected in vascular smooth muscle cells.
Specimen 3b: embryonic day 10.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally intact. Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS17: 4th arch artery Present Regionally restricted 3b' , 3b , 3b''' In the structurally-intact artery of null embryos, normal expression was detected in vascular smooth muscle cells.
Specimen 3c: embryonic day 10.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally defective. Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS17: 4th arch artery Trace Regionally restricted 3c''' , 3c , 3c' In the structurally-defective artery, immunopositive cells were nearly absent.
Specimen 3d: embryonic day 11.5 (more )
Note: Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS19: 4th arch artery Present Regionally restricted 3d , 3d' , 3d''' Expression was detected in vascular smooth muscle cells.
Specimen 3e: embryonic day 11.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally intact. Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS19: 4th arch artery Present Regionally restricted 3e' , 3e , 3e''' In the structurally-intact artery of null embryos, normal expression was detected in vascular smooth muscle cells.
Specimen 3f: embryonic day 11.5; Hey1tm1Ona/Hey1tm1Ona (more )
Note: Structurally defective. Double labeled: green - Tagln; red - Pecam1 (assay MGI:6236304).
Structure Level Pattern Image Note
TS19: 4th arch artery Trace Regionally restricted 3f , 3f''' , 3f' In the structurally-defective artery, immunopositive cells were nearly absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory