Tg(KRT18-DPP4)3Pbmj
Transgene Detail
|
|
| Symbol: |
Tg(KRT18-DPP4)3Pbmj |
| Name: |
transgene insertion 3, Paul B McCray Jr |
| MGI ID: |
MGI:6402178 |
| Synonyms: |
K18-hDPP4 |
| Transgene: |
Tg(KRT18-DPP4)3Pbmj Location: unknown
|
| Alliance: |
Tg(KRT18-DPP4)3Pbmj page
|
|
| Strain of Origin: |
C57BL/6J x SJL/J
|
|
| Transgene Type: |
|
Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(KRT18-DPP4)3Pbmj expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
DPP4 (1803) |
|
|
|
| |
|
Mutation details: A FLAG epitope-tagged human DPP4 cDNA is under the control of the human cytokeratin 18 promoter. The promoter directs expression of the Middle East respiratory coronavirus receptor in airway and alveolar epithelial cells, as well as epithelial of the liver, kidney, and gastrointestinal tract, and some nervous system cells. Four lines were generated.
(J:285467)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:285467 Li K, et al., Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. J Infect Dis. 2016 Mar 1;213(5):712-22 |
| All: |
7 reference(s) |
|
Analysis Tools
