Tg(FOXJ1-ACE2)1Rba Transgene Detail MGI Mouse (MGI:6415223)

Tg(FOXJ1-ACE2)1Rba
Transgene Detail

Summary

Symbol:	Tg(FOXJ1-ACE2)1Rba
Name:	transgene insertion 1, Ralph Baric
MGI ID:	MGI:6415223
Synonyms:	HFH4-ACE2, HFH4-hACE2
Transgene:	Tg(FOXJ1-ACE2)1Rba Location: unknown
Alliance:	Tg(FOXJ1-ACE2)1Rba page

Transgene
origin

Strain of Origin:

(C3H x C57BL/6)F1

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(FOXJ1-ACE2)1Rba expresses 1 gene

Mutation details: Human angiotensin-converting enzyme-2 (ACE2) in is expressed under the control of human FOXJ1 gene. Expression was observed in the lungs, and other tissues including brain, liver, kidney, and gastrointestinal tract. (J:287092)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:287092 Menachery VD, et al., SARS-like WIV1-CoV poised for human emergence. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3048-53
All:	17 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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