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Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416257
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (#9587)
Detection system: Alexa Fluor 647
Results
Specimen 1E: embryonic day 12.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Triple labeled: magenta - Ctnnb1; red - Nf2 (assay MGI:6416155); green - Tjp1 (assay MGI:6416258).
Structure Level Pattern Image Note
TS20: neocortex Present 1E Beta-catenin , 1E Merge Expression was detected in apical junctions in neural progenitor cells.
Specimen 1F: embryonic day 12.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Triple labeled: magenta - Ctnnb1; red - Nf2 (assay MGI:6416155); green - Tjp1 (assay MGI:6416258).
Structure Level Pattern Image Note
TS20: neocortex Present 1F Beta-catenin , 1F Merge Loss of Nf2 did not affect the localization of Ctnnb1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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