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Gene Expression Data
Assay Details
Assay
Reference: J:270838 Wiederstein JL, et al., Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown. Cell Rep. 2018 May 1;23(5):1342-1356
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6458593
Gene symbol: Vcp
Gene name: valosin containing protein
Antibody: anti-methyl VCP/p97 (Lys315)
Detection system: Alexa Fluor
Results
Specimen 5F 3me-97 wild type (upper): postnatal adult (more )
Note: Double labeled: blue - 3me-97 (K315) (Vcp); red - Myh7 (assay MGI:6458580).
Structure Level Pattern Image Note
TS28: soleus Present 5F wild type (upper right) , 5F wild type (upper left)
Specimen 5F 3me-97 wild type (lower): postnatal adult (more )
Note: Double labeled: blue - 3me-97 (K315) (Vcp); red - Myh7 (assay MGI:6458580).
Structure Level Pattern Image Note
TS28: soleus Present 5F wild type (lower right) , 5F wild type (lower left)
Specimen 5F 3me-97 Mettl21c -/- (upper): postnatal adult; Mettl21ctm1.1Krug/Mettl21ctm1.1Krug (more )
Note: Double labeled: blue - 3me-97 (K315) (Vcp); red - Myh7 (assay MGI:6458580).
Structure Level Pattern Image Note
TS28: soleus Weak Regionally restricted 5F Mettl21c -/- (upper right) , 5F Mettl21c -/- (upper left) Reduced expression in slow fibers.
Specimen 5F 3me-97 Mettl21c -/- (lower): postnatal adult; Mettl21ctm1.1Krug/Mettl21ctm1.1Krug (more )
Note: Double labeled: blue - 3me-97 (K315) (Vcp); red - Myh7 (assay MGI:6458580).
Structure Level Pattern Image Note
TS28: soleus Weak Regionally restricted 5F Mettl21c -/- (lower right) , 5F Mettl21c -/- (lower left) Reduced expression in slow fibers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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