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Gene Expression Data
Assay Details
Assay
Reference: J:163028 Mulder J, et al., Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon. Eur J Neurosci. 2010 Jun;31(12):2166-77
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6491315
Gene symbol: Scgn
Gene name: secretagogin, EF-hand calcium binding protein
Antibody: anti-Scgn (HPA006641)
Detection system: Secondary antibody coupled to cyanine dye
Results
Specimen 2A: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; green - Dcx (assay MGI:6491322)
Structure Level Pattern Image Note
TS21: gonad Present 2A
TS21: heart Present 2A
TS21: metanephros Present 2A
TS21: pancreas Present 2A
TS21: stomach Present Regionally restricted 2A Expression is seen in putative enteroendocrine cells.
TS21: dorsal root ganglion Absent 2A
Specimen 2C: embryonic day 13.0 (more )
Note: Triple labeled: green - Scgn; red - Dcx (assay MGI:6491322); blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS21: dorsal root ganglion Absent 2C
Specimen 3A: embryonic day 11.0 (more )
Note: Double labeled: red - Scgn; green - Nes (RC2; assay MGI:6491319)
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 3A Expression is seen in postmitotic neurons in the anterior wall forming the olfactory bulb.
Specimen 3B: embryonic day 11.0 (more )
Note: Triple labeled: red - Scgn; green - Pou3f3 (Brn1; assay MGI:6491317); blue - Nes (RC2; assay MGI:6491319)
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 3B Expression is seen in the pallidal differentiation zone at the basal surface of the telencephalic vesicle. Double labeling indicates that the expressing cells are neither neocortical neurons nor radial glia.
Specimen 3C: embryonic day 12.0 (more )
Note: Triple labeled: red - Scgn; green - Dcx (assay MGI:6491322); blue - Nes (assay MGI:6491320)
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3C Expression is seen in cells transiting in the differentiation zone that commits neurons to the prospective globus pallidus. Double labeling suggests these are postmitotic, non-pyramidial neurons.
Specimen 3D: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3D Expression is present in neurons in subnuclei of the extended amygdala.
Specimen 3D1: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3D1 Expression is present in neurons in subnuclei of the extended amygdala.
Specimen 3D2: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3D2 Expression is present in neurons in subnuclei of the extended amygdala.
Specimen 3D3: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3D3 Expression is present in neurons in subnuclei of the extended amygdala.
Specimen 3D4: embryonic day 13.0 (more )
Note: Triple labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321); green - Dcx (assay MGI:6491322)
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted 3D4 Expression is present in neurons in subnuclei of the extended amygdala.
Specimen 3E: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: main olfactory bulb layer Present Regionally restricted 3E Expression is seen in the granular layer.
Specimen 3E1: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: main olfactory bulb layer Present Regionally restricted 3E1 Expression is seen in the granular layer.
Specimen 3E2: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: amygdala Present 3E2 Expression is seen in neurons populating the prospective amygdala.
Specimen 3E3: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: amygdala Present 3E3 Expression is seen in neurons populating the prospective amygdala.
TS23: diencephalon Present Regionally restricted 3E3 Expression is seen in neurons that are likely destined to the interstitial nucleus of the posterior limb of the anterior commissure (IPAC) and substantia innominata (SI).
Specimen 3E4: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: amygdala Present 3E4 Expression is seen in neurons populating the prospective amygdala.
TS23: diencephalon Present Regionally restricted 3E4 Expression is seen in neurons that are likely destined to the interstitial nucleus of the posterior limb of the anterior commissure (IPAC) and substantia innominata (SI).
Specimen 3E5: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: amygdala Present 3E5 Expression is seen in neurons populating the prospective amygdala.
TS23: diencephalon Present Regionally restricted 3E5 Expression is seen in neurons that are likely destined to the interstitial nucleus of the posterior limb of the anterior commissure (IPAC) and substantia innominata (SI).
Specimen 3E6: embryonic day 15.0 (more )
Note: Double labeled: red - Scgn; blue - Tubb3 (assay MGI:6491321)
Structure Level Pattern Image Note
TS23: amygdala Present 3E6 Expression is seen in neurons populating the prospective amygdala.
Specimen 5A: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: anterior olfactory nucleus Present 5A
Specimen 5A1: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: pallidum Present Regionally restricted 5A1 Expressing cells are seen in the ventral pallidum.
Specimen 5A2: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: pallidum Present Regionally restricted 5A2 Expressing neurons are seen in the ventral pallidum.
TS27: anterior commissure Present Regionally restricted 5A2 Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
TS27: bed nucleus of stria terminalis Present 5A2
Specimen 5A3: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: pallidum Present Regionally restricted 5A3 Expressing neurons are seen in the ventral pallidum.
TS27: anterior commissure Present Regionally restricted 5A3 Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
TS27: bed nucleus of stria terminalis Present 5A3
TS27: nucleus of diagonal band Present Regionally restricted 5A3 Expressing neurons are seen in the nucleus of the horizontal limb of the diagonal bnad.
Specimen 5A4: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 5A4 Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
TS27: telencephalon Present Regionally restricted 5A4 Expressing neurons are seen in the dorsal substantia innominata.
TS27: cortical amygdaloid nucleus Present Regionally restricted 5A4 Expresssing neurons are seen in the cortical amygdaloid area.
TS27: amygdala Present 5A4 Expressing neurons are seen in the extended amygdala.
TS27: paraventricular thalamic nucleus Present 5A4
Specimen 5A5: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 5A5 Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
TS27: telencephalon Present Regionally restricted 5A5 Expressing neurons are seen in the dorsal substantia innominata.
TS27: central amygdaloid nucleus Present 5A5
TS27: cortical amygdaloid nucleus Present Regionally restricted 5A5 Expresssing neurons are seen in the cortical amygdaloid area.
TS27: paraventricular thalamic nucleus Present 5A5
Specimen 5A6: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: telencephalon Present Regionally restricted 5A6 Expressing neurons are seen in the dorsal substantia innominata.
TS27: central amygdaloid nucleus Present 5A6
TS27: cortical amygdaloid nucleus Present Regionally restricted 5A6 Expresssing neurons are seen in the cortical amygdaloid area.
TS27: basolateral amygdaloid nucleus Present 5A6
TS27: hypothalamus periventricular zone Present 5A6 Expressing neurons are seen in the periventricular hypothalamic nucleus.
Specimen 5A7: postnatal newborn (more )
Note: Schematic presentation of the distribution of expressing neurons along the anterior-posterior axis of the brain.
Structure Level Pattern Image Note
TS27: bed nucleus of stria terminalis Present Regionally restricted 5A7 Expressing neurons are seen in the intra-amygdaloid division of the bed nucleus of the stria terminalis.
TS27: subthalamic nucleus Present 5A7
TS27: basomedial amygdaloid nucleus Present 5A7
Specimen 5C: embryonic day 13.0 (more )
Note: Double labeled: red - Scgn; green - Pou3f3 (Brn1; assay MGI:6491317)
Structure Level Pattern Image Note
TS21: main olfactory bulb Present Regionally restricted 5C Expression is seen in the olfactory bulb; double labeling shows these are GABAergic cells.
Specimen 5C1: embryonic day 13.0 (more )
Note: Double labeled: green - Scgn; blue - Ncam1 (assay MGI:6491318)
Structure Level Pattern Image Note
TS21: main olfactory bulb Present 5C1
Specimen 5D: postnatal newborn; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS27: amygdala Present Regionally restricted 5D Expression is seen in GABAergic neurons in the extended amygdala.
Specimen 5D1: postnatal newborn; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS27: central amygdaloid nucleus Present Regionally restricted 5D1 Expression is seen in GABAergic neurons.
Specimen 7B: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS28: amygdala Present Regionally restricted 7B Expressing neurons are seen in the extended amygdala.
TS28: bed nucleus of stria terminalis Present Regionally restricted 7B Expressing neurons are seen in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC).
TS28: central amygdaloid nucleus Present 7B
TS28: medial amygdaloid nucleus Present 7B
Specimen 7E: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS28: central amygdaloid nucleus Present Regionally restricted 7E Expression is seen in a subset of GABAergic neurons.
Specimen 7E1: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS28: anterior commissure Present Regionally restricted 7E1 Expression is seen in multipolar cells in the interstitial nucleus of the posterior limb of the anterior commissure (IPAC); they are not GABAergic.
Specimen 7E2: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Double labeled: red - Scgn; green - Gad1 reporter (GAD67; assay MGI:6491316)
Structure Level Pattern Image Note
TS28: bed nucleus of stria terminalis Present Regionally restricted 7E2 Expression is seen in large-diameter, bifurcating neurons in the intra-amygdaloid division of the bed nucleus of the stria terminalis; they are not GABAergic.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory