Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:231231 Abby E, et al., Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6695760
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved caspase 3
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

3d +/+ ©

Specimen 3d +/+: embryonic day 18.5 (more

)
Note: Double labeled: brown - Casp3; magenta - Ddx4 (assay MGI:6695761).

Structure	Level	Pattern	Image	Note
TS26: oocyte	Absent		3d +/+

3d -/- ©

Specimen 3d -/-: embryonic day 18.5; Meioc^{tm1a(KOMP)Wtsi}/Meioc^{tm1a(KOMP)Wtsi} (more

)
Note: Double labeled: brown - Casp3; magenta - Ddx4 (assay MGI:6695761).

Structure	Level	Pattern	Image	Note
TS26: oocyte	Present		3d -/-

Specimen 4f +/+: postnatal day 3 (more

)

Structure	Level	Pattern	Image	Note
TS27: meiotic germ cell of ovary	Ambiguous		4f Meioc+/+ c-Casp3

Specimen 4f -/-: postnatal day 3; Meioc^{tm1a(KOMP)Wtsi}/Meioc^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS27: meiotic germ cell of ovary	Present		4f Meioc-/- c-Casp3	Numerous germ cells were stained with the marker for apoptosis.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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