About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:237701 Saare M, et al., Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis. PLoS One. 2015;10(6):e0129131
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6864139
Gene symbol: Numa1
Gene name: nuclear mitotic apparatus protein 1
Antibody: anti-NuMA
Detection system: Alexa Fluor
Results
Specimen 3B/C: postnatal adult (more )
Note: germinal vesicle stage. Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted 3B , 3C Broadly expressed in germinal vesicle.
Specimen 3b/c: postnatal adult (more )
Note: Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted 3c , 3b Expression partially co-localizing with RIC8 (Ric8a).
Specimen 3E/F: postnatal adult (more )
Note: germinal vesicle breakdown. Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS28: secondary oocyte Present Regionally restricted 3E , 3F After germinal vesicle breakdown, expression sarting to condense around chromoatin.
Specimen 3e/f: postnatal adult (more )
Note: Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS28: secondary oocyte Present Regionally restricted 3e , 3f Expression much wider compared to that of RIC8 (Ric8a).
Specimen 5B/C: postnatal adult (more )
Note: anaphase/telophase of meiosis I. Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS28: oocyte Present Regionally restricted 5B , 5C When chromosomes segregate, expression translocated to spindle midzone.
Specimen 6B/C: embryonic day 0.5 (more )
Note: pronuclear stage. Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 6C , 6B Expression broadly localized in pronucleus.
Specimen 6b/c: embryonic day 0.5 (more )
Note: Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 6b , 6c No overlap with RIC8 (Ric8a).
Specimen 7K/L: embryonic day 1.0 (more )
Note: Triple labeled: red - NUMA (Numa1); green - RIC8 (Ric8a assay MGI:6864135); blue - DAPI.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Regionally restricted 7L , 7K Expression in nucleus of blastomeres. No overlap with RIC8 (Ric8a) in cortex region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory