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Gene Expression Data
Assay Details
Assay
Reference: J:310857 Welcker D, et al., Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6883742
Gene symbol: Hmcn1
Gene name: hemicentin 1
Antibody: anti-Hmcn1
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2A/A': postnatal day 1 (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS27: dermis Present Widespread 2A , 2A'
Specimen 2C/C': postnatal adult (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS28: dermis Strong Regionally restricted 2C , 2C' Concentrated on the dermal side of the basement membrane, but not detectable in the lower dermis.
Specimen 2E/E': postnatal day 1 (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS27: hindlimb tendon Present 2E' , 2E
Specimen 2G: postnatal adult (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS28: hindlimb tendon Present 2G
Specimen 2I/I': postnatal day 1 (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS27: perichondrium Present 2I , 2I' upper , 2I' lower
TS27: dermis Present Regionally restricted 2I' lower , 2I , 2I' upper Expressed at the dermal side of basement membrane.
Specimen 3E: postnatal newborn (more )
Note: Double labeled: red - Hmcn1; green - Lama2 (assay MGI:6885595).
Structure Level Pattern Image Note
TS27: dermis Present 3E
Specimen 3F: postnatal newborn; Hmcn1tm1.1Hamm/Hmcn1tm1.1Hamm (more )
Note: Double labeled: red - Hmcn1; green - Lama2 (assay MGI:6885595).
Structure Level Pattern Image Note
TS27: dermis Absent 3F
Specimen 3G: postnatal newborn (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS27: lower leg muscle Present 3G
Specimen 3H: postnatal newborn; Hmcn1tm1.1Hamm/Hmcn1tm1.1Hamm (more )
Note: Double labeled: red - Hmcn1; green - Tnc (assay MGI:6885592).
Structure Level Pattern Image Note
TS27: lower leg muscle Absent 3H
Specimen 4S/S': embryonic day 14.5 (more )
Note: Double labeled: red - Hmcn1; green - Lama2 (assay MGI:6885595).
Structure Level Pattern Image Note
TS22: extracellular matrix Present 4S , 4S'
TS22: metanephros epithelium Present 4S , 4S'
Specimen 4T/T': embryonic day 14.5; Hmcn1tm1.1Hamm/Hmcn1tm1.1Hamm (more )
Note: Double labeled: red - Hmcn1; green - Lama2 (assay MGI:6885595).
Structure Level Pattern Image Note
TS22: extracellular matrix Absent 4T' , 4T
TS22: metanephros epithelium Absent 4T' , 4T
Specimen 6A/B: postnatal (more )
Note: Double labeled: red - Hmcn1; green - Lama2 (assay MGI:6885595).
Structure Level Pattern Image Note
TS28: basement membrane of epithelium Present 6B , 6A
Specimen S2_1A/A'/A": postnatal day 1 (more )
Note: Double labeled: red - Hmcn1; green - Hmcn2 (assay MGI:6883741).
Structure Level Pattern Image Note
TS27: dermis Present Widespread S2_1A , S2_1A'
TS27: hindlimb tendon Present S2_1A" , S2_1A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory