Cdkn1a Immunohistochemistry Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:270680 Han X, et al., The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development. J Biol Chem. 2018 Sep 21;293(38):14572-14584
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7334991
Gene symbol:	Cdkn1a
Gene name:	cyclin dependent kinase inhibitor 1A

Antibody:	anti-p21
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1E (bottom) upper 1st molar E13 ©

Specimen 1E (bottom) upper 1st molar E13: embryonic day 13.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS21: upper jaw molar	Present		1E (bottom) upper 1st molar E13

1E (bottom) upper 1st molar E14 ©

Specimen 1E (bottom) upper 1st molar E14: embryonic day 14.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar	Present		1E (bottom) upper 1st molar E14

1E (bottom) upper 1st molar E16 ©

Specimen 1E (bottom) upper 1st molar E16: embryonic day 16.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS24: upper jaw molar	Present	Regionally restricted	1E (bottom) upper 1st molar E16
TS24: secondary enamel knot	Present		1E (bottom) upper 1st molar E16

1E (bottom) upper 1st molar E14 enlargement ©

Specimen 1E (bottom) upper 1st molar E14 enlargement: embryonic day 14.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS22: primary enamel knot	Present		1E (bottom) upper 1st molar E14 enlargement

1E (bottom) lower 1st molar E13 ©

Specimen 1E (bottom) lower 1st molar E13: embryonic day 13.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS21: lower jaw molar	Present		1E (bottom) lower 1st molar E13

1E (bottom) lower 1st molar E14 ©

Specimen 1E (bottom) lower 1st molar E14: embryonic day 14.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS22: upper jaw molar	Present		1E (bottom) lower 1st molar E14

1E (bottom) lower 1st molar E16 ©

Specimen 1E (bottom) lower 1st molar E16: embryonic day 16.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS24: lower jaw molar	Present	Regionally restricted	1E (bottom) lower 1st molar E16
TS24: secondary enamel knot	Present		1E (bottom) lower 1st molar E16

1E (bottom) lower 1st molar E14 enlargement ©

Specimen 1E (bottom) lower 1st molar E14 enlargement: embryonic day 14.0 (more

)
Note: Double labeled: green - p21 (Cdkn1a); red - perlecan (Hspg2 assay MGI:7334990).

Structure	Level	Pattern	Image	Note
TS22: primary enamel knot	Present		1E (bottom) lower 1st molar E14 enlargement

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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