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Gene Expression Data
Assay Details
Assay
Reference: J:331142 Han P, et al., Cbln1 regulates axon growth and guidance in multiple neural regions. PLoS Biol. 2022 Nov;20(11):e3001853
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388454
Gene symbol: Lhx2
Gene name: LIM homeobox protein 2
Antibody: anti-Lhx2
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1B Lhx2: embryonic day 10.5 (more )
Note: Double labeled: red - Lhx2; green - Cbln1 (assay MGI:7388453).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord commissural neuron Present Regionally restricted 1B (merged left) , 1B' , 1B Lhx2 Expression in dI1 dorsal commissural neurons.
Specimen 1C Lhx2: embryonic day 11.5 (more )
Note: Double labeled: red - Lhx2; green - Cbln1 (assay MGI:7388453).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord commissural neuron Present Regionally restricted 1C (merged left) , 1C Lhx2 , 1C' Expression in dI1 dorsal commissural neurons.
Specimen 1D Lhx2: embryonic day 12.5 (more )
Note: Double labeled: red - Lhx2; green - Cbln1 (assay MGI:7388453).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord commissural neuron Present Regionally restricted 1D (merged upper) , 1D Lhx2 , 1D' Expression in dI1 dorsal commissural neurons.
Specimen S2A Cbln1fl/fl Lhx2: embryonic day 11.5; Cbln1tm1.1Sjj/Cbln1tm1.1Sjj (more )
Note: Double labeled: green - Lhx2; red - Lhx9 (assay MGI:7388464).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord commissural neuron Present Regionally restricted S2A Cbln1fl/fl Lhx2 , S2A Cbln1fl/fl (merged) Expression in dI1 dorsal commissural neurons.
Specimen S2A Wnt1-Cre Lhx2: embryonic day 11.5; Cbln1tm1.1Sjj/Cbln1tm1.1Sjj, H2az2Tg(Wnt1-cre)11Rth/0 (more )
Note: Conditional mutant. Double labeled: green - Lhx2; red - Lhx9 (assay MGI:7388464).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord commissural neuron Present Regionally restricted S2A Wnt1-Cre (merged) , S2A Wnt1-Cre Lhx2 Patterning of dI1 dorsal commissural neurons is not disturbed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory