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Gene Expression Data
Assay Details
Assay
Reference: J:237224 Kim JY, et al., Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437602
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 (AB5809)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4G: embryonic day 16.5; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Double labeled: green - Sox9; red - Mitf (assay MGI:7437603).
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Present 4G
Specimen 4H: embryonic day 16.5; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Present Regionally restricted 4H Expression was altered or absent in ectopic, multilayered epithelium.
Specimen 8C/D: embryonic day 16.5; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Triple labeled: green - Sox9; blue - Yap1 (assay MGI:7437625); red - BrdU.
Structure Cell Type Level Pattern Image Note
TS24: neural retina retinal progenitor cell Present Regionally restricted 8C , 8D Expressed in the outer neuroblastic layer.
Specimen 8G/H: embryonic day 16.5; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Triple labeled: green - Sox9; blue - Yap1 (assay MGI:7437625); red - BrdU.
Structure Cell Type Level Pattern Image Note
TS24: neural retina retinal progenitor cell Present Regionally restricted 8G , 8H Expressed in the outer neuroblastic layer, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory