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Gene Expression Data
Assay Details
Assay
Reference: J:202344 Lesko MH, et al., Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7447405
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase3
Detection system: Secondary antibody
Results
Specimen S3C/D: postnatal day 17 (more )
Note: Catagen hair follicles. Double labeled: red - Casp3; green - Krt14 (assay MGI:7447382).
Structure Level Pattern Image Note
TS28: hair follicle Present S3D , S3C

Specimen S3E: embryonic day 18.5; Sox2tm4.1Skn/Sox2tm4.1Skn (more )
Note: Triple labeled: red - Casp3; white - Krt14 (assay MGI:7447393); green - Krt8 (assay MGI:7447388).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer Merkel cell Absent S3E

Specimen S3F: embryonic day 18.5; Sox2tm4.1Skn/Sox2tm4.1Skn, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Casp3; white - Krt14 (assay MGI:7447393); green - Krt8 (assay MGI:7447388).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer Merkel cell Absent S3F No increased apoptosis was seen.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory