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Gene Expression Data
Assay Details
Assay
Reference: J:184591 Aoyama M, et al., Spatial Restriction of Bone Morphogenetic Protein Signaling in Mouse Gastrula through the mVam2-Dependent Endocytic Pathway. Dev Cell. 2012 Jun 12;22(6):1163-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464741
Gene symbol: Lamp2
Gene name: lysosomal-associated membrane protein 2
Antibody: anti-lamp2
Detection system: Secondary antibody
Results
Specimen 1C WT sagittal: embryonic day 6.5 (more )
Note: Double labeled: red - Lamp2; green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Regionally restricted 1C WT sagittal Ring-like pattern of expression in limiting membranes of apical vacuoles in visceral endoderm.

Specimen 1C WT parasagittal: embryonic day 6.5 (more )
Note: Double labeled: red - Lamp2; green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Regionally restricted 1C WT parasagittal Ring-like pattern of expression in limiting membranes of apical vacuoles in visceral endoderm.

Specimen 1C mVam2-/- sagittal: embryonic day 6.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Double labeled: red - Lamp2; green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Punctate 1C mVam2-/- sagittal Punctate pattern of expression.

Specimen 1C mVam2-/- parasagittal: embryonic day 6.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Double labeled: red - Lamp2; green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Punctate 1C mVam2-/- parasagittal Punctate pattern of expression.

Specimen 1D WT sagittal: embryonic day 6.5 (more )
Note: Double labeled: red - Lamp2; green - Snx1 (assay MGI:7464746).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Regionally restricted 1D WT sagittal Ring-like pattern of expression in limiting membranes of apical vacuoles in visceral endoderm.

Specimen 1D WT parasagittal: embryonic day 6.5 (more )
Note: Double labeled: red - Lamp2; green - Snx1 (assay MGI:7464746).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Regionally restricted 1D WT parasagittal Ring-like pattern of expression in limiting membranes of apical vacuoles in visceral endoderm.

Specimen 1D mVam2-/- sagittal: embryonic day 6.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Double labeled: red - Lamp2; green - Snx1 (assay MGI:7464746).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Punctate 1D mVam2-/- sagittal Punctate pattern of expression.

Specimen 1D mVam2-/- parasagittal: embryonic day 6.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Double labeled: red - Lamp2; green - Snx1 (assay MGI:7464746).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Punctate 1D mVam2-/- parasagittal Punctate pattern of expression.

Specimen 6A lamp2 WT: embryonic day 6.2 (more )
Note: Triple labeled: blue - Lamp2; red - Bmpr1a (assay MGI:7464760); green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 6A WT inset , 6A WT

Specimen 6A lamp2 mVam2-/-: embryonic day 6.2; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Triple labeled: blue - Lamp2; red - Bmpr1a (assay MGI:7464760); green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 6A mVam2-/- inset , 6A mVam2-/-

Specimen S5A lamp2 wild-type: embryonic day 6.0 (more )
Note: Triple labeled: blue - Lamp2; red - Bmpr1a (assay MGI:7464760); green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS8: primitive endoderm Present Regionally restricted S5A Bmpr1a/lamp2/rab7 wild-type Expression in limiting membranes of apical vacuoles.

Specimen S5A lamp2 mVam2-/-: embryonic day 6.0; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Note: Triple labeled: blue - Lamp2; red - Bmpr1a (assay MGI:7464760); green - Rab7 (assay MGI:7464737).
Structure Level Pattern Image Note
TS8: primitive endoderm Present S5A Bmpr1a/lamp2/rab7 mVam2-/-


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory