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Gene Expression Data
Assay Details
Assay
Reference: J:271281 Bowles J, et al., Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7466642
Gene symbol: Hsd3b
Gene name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase cluster
Antibody: anti-HSD3B
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A Wt HSD3B: embryonic day 14.5 (more )
Note: Double labeled: green - Hsd3b; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS22: Leydig cell Leydig cell Present 4A XY Wt right , 4A XY Wt right inset

Specimen 4A KO HSD3B: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Double labeled: green - Hsd3b; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS22: Leydig cell Leydig cell Present 4A XY KO right , 4A XY KO right inset The number of expressing cells is decreased in the mutant relative to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory