Shh Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:156970 Mikels A, et al., Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7481221
Gene symbol:	Shh
Gene name:	sonic hedgehog

Antibody:	anti-Shh
Detection system:	Secondary antibody

Results

Specimen 5A Ror2^+/-: embryonic day 16.5; Ror2^tm1Ymi/Ror2⁺ (more

)
Note: Double labeled: green - Shh; red - Ror2 (assay MGI:7481219).

Structure	Level	Pattern	Image	Note
TS24: lung epithelium	Present		5A Ror2/Shh 20X Ror2^+/- , 5A Ror2/Shh 10X Ror2^+/- , 5A Ror2/Shh 40X Ror2^+/-

Specimen 5A Ror2^-/-: embryonic day 16.5; Ror2^tm1Ymi/Ror2^tm1Ymi (more

)
Note: Double labeled: green - Shh; red - Ror2 (assay MGI:7481219).

Structure	Level	Pattern	Image	Note
TS24: lung epithelium	Present		5A Ror2/Shh 40X Ror2^-/- , 5A Ror2/Shh 10X Ror2^-/- , 5A Ror2/Shh 20X Ror2^-/-	There were no major differences in the staining pattern or intensity in this mutant compared to wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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