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Gene Expression Data
Assay Details
Assay
Reference: J:225328 Ren AJ, et al., ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons. Nat Commun. 2014;5:4984
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7484620
Gene symbol: Zbtb20
Gene name: zinc finger and BTB domain containing 20
Results
Specimen S1 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Absent S1_E12.5 ZBTB20_
Specimen S1 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Weak S1_E13.5 ZBTB20 Expression first detected at E13.5.
Specimen S1 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Present S1_E14.5 ZBTB20 Expression increased by E14.5.
Specimen S1 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present S1_E15.5 ZBTB20
Specimen 1a ZBTB20: postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Nefh (assay MGI:7484621).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Weak Regionally restricted 1a Merged , 1a ZBTB20 Expression hardly detected in large neurofilament-expressing neurons.
Specimen 1b ZBTB20: postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Prph (assay MGI:7484622).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Strong Regionally restricted 1b ZBTB20 , 1b Merged Highly expressed in most small peripherin-expressing neurons.
Specimen 1c ZBTB20: postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Scn10a (assay MGI:7484624).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1c Merged , 1c ZBTB20 Expression in majority of Nav1.8-expressing neurons.
Specimen 2c ZBTB20 Control: postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Scn10a (assay MGI:7484624).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present 2c Control
Specimen 2c ZBTB20 PN-ZB20KO: postnatal adult; Scn10atm2(cre)Jwo/Scn10a+, Zbtb20tm1Wpjz/Zbtb20tm1Wpjz (more )
Note: Conditional mutant. Floxed/Cre-negative, non-floxed Cre-positive or wild-type mice were used as littermate controls. Double labeled: red - Zbtb20; green - Scn10a (assay MGI:7484624).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Weak Regionally restricted 2c PN-ZBTB20 Expression in only a minority of Nav1.8-expressing neurons.
Specimen 5d ZBTB20 (left): postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Trpv1 (assay MGI:7484627).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 5d TRPV1/ZBTB20 , 5d TRPV1/ZBTB20 inset Expression in majority of neurons expressing Trpv1.
Specimen 5d ZBTB20 (middle): postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Trpa1 (assay MGI:7484629).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 5d TRPA1/ZBTB20 inset , 5d TRPA1/ZBTB20 Expression in majority of neurons expressing Trpa1.
Specimen 5d ZBTB20 (right): postnatal adult (more )
Note: Double labeled: red - Zbtb20; green - Trpm8 (assay MGI:7484630).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 5d TRPM8/ZBTB20 inset , 5d TRPM8/ZBTB20 Expression in majority of neurons expressing Trpm8.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory