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Gene Expression Data
Assay Details
Assay
Reference: J:213958 Lang RA, et al., p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Development. 2014 Aug;141(16):3177-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486717
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (#610153), clone 14
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A left: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present 1A left Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1A right: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - F-actin staining.
Structure Level Pattern Image Note
TS16: lens placode Present 1A right Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1F: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present 1F Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1G: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present 1G A more intense signal at the filament intersection was also observed.
Specimen 1H: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - F-actin staining.
Structure Level Pattern Image Note
TS16: lens placode Present 1H Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1J: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: head surface ectoderm Present 1J Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1K: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - F-actin staining.
Structure Level Pattern Image Note
TS16: head surface ectoderm Present 1K Expressed in the zonula adherens associated with the actomyosin filaments.
Specimen 1L: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: olfactory placode Present 1L Expressed in the zonula adherens associated with the actomyosin filaments. A more intense signal at the filament intersection was also observed in cells within the periphery.
Specimen 1O: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: olfactory placode Present 1O Expressed in the zonula adherens associated with the actomyosin filaments. A more intense signal at the filament intersection was also observed.
Specimen 5A left: embryonic day 10.0; Ctnnd1tm1Abre/Ctnnd1+ (more )
Note: Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present 5A left merge , 5A left beta-cat Locally displaced bicellular junctions were seen. The displacement was significantly greater than the width of a straight filament-nonassociated junction (see Fig. 5B).
Specimen 5A right: embryonic day 10.0; Ctnnd1tm1Abre/Ctnnd1+, Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Note: Conditional mutant. Double labeled: green - Ctnnb1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present 5A right merge , 5A right beta-cat Filament-associated bicellular junctions did not curve and on average were not significantly displaced (see Fig. 5B).
Specimen S3A: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnb1; red - Shroom3 (assay MGI:7486722).
Structure Level Pattern Image Note
TS16: lens placode Present S3A right , S3A merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory