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Gene Expression Data
Assay Details
Assay
Reference: J:333946 Hattori Y, et al., CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7488359
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: anti-LYVE1 (ALY7) (14-0443-82)
Detection system: Secondary antibody
Results
Specimen 1F E12.5 LYVE1: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: magenta - Lyve1; green - Mrc1 (assay MGI:7488358).
Structure Cell Type Level Pattern Image Note
TS20: brain meninges meningeal macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS20: lateral ventricle central nervous system macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS20: pallium central nervous system macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.

Specimen 1F E13.5 LYVE1: embryonic day 13.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: magenta - Lyve1; green - Mrc1 (assay MGI:7488358).
Structure Cell Type Level Pattern Image Note
TS21: telencephalon meninges meningeal macrophage Present Regionally restricted 1F E13.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS21: lateral ventricle central nervous system macrophage Present Regionally restricted 1F E13.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS21: pallium Present Regionally restricted 1F E13.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.

Specimen S1C E14.5 LYVE1: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: magenta - Lyve1; green - Mrc1 (assay MGI:7488358).
Structure Cell Type Level Pattern Image Note
TS22: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS22: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS22: pallium central nervous system macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.

Specimen S1C E15.5 LYVE1: embryonic day 15.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: magenta - Lyve1; green - Mrc1 (assay MGI:7488358).
Structure Cell Type Level Pattern Image Note
TS23: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS23: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS23: pallium central nervous system macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.

Specimen S1C E16.5 LYVE1: embryonic day 16.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: magenta - Lyve1; green - Mrc1 (assay MGI:7488358).
Structure Cell Type Level Pattern Image Note
TS24: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS24: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS24: pallium central nervous system macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory