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Gene Expression Data
Assay Details
Assay
Reference: J:276652 Fang Q, et al., Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506985
Gene symbol: Cfl1
Gene name: cofilin 1, non-muscle
Antibody: anti-p-cofilin (hSer3)-R (sc-12912)
Assay notes: Fixation with 4% polyoxymethylene.
Results
Specimen 6c p-cofilin WT: postnatal day 30 (more )
Note: Double labeled: red - Cfl1 (p-cofilin); green - Myo7a (assay MGI:7506974).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlea auditory hair cell Present 6c p-cofilin WT , 6c Merged WT (lower) No difference in expression from apical to basal turns.
Specimen 6c p-cofilin DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Cfl1 (p-cofilin); green - Myo7a (assay MGI:7506974).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlea auditory hair cell Weak 6c p-cofilin DKO , 6c Merged DKO (lower) Expression signifiantly decreased compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
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