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Gene Expression Data
Assay Details
Assay
Reference: J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7507063
Gene symbol: Patj
Gene name: PATJ, crumbs cell polarity complex component
Antibody: Anti-Patj
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 8C: postnatal day 6; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: red - Patj; green - Mki67 (assay MGI:7507060).
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8C Expression was detected in the apical region.
Specimen 8D: postnatal day 6; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: red - Patj; green - Mki67 (assay MGI:7507060).
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8D Immunopositive ectopic cells co-stained with Mki67-positive cells at the periphery of the developing retina.
Specimen S1L: embryonic day 12.5; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted S1L Expression was detected in the subapical region.
Specimen S1O: embryonic day 12.5; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted S1O Expression was detected in the subapical region and the cytoplasm of some cells, thought to be mitotic cells, located at the outer limiting membrane.
Specimen S2A: postnatal day 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: red - Patj; green - Mpdz (assay MGI:7506785).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S2C , S2A Immunostaining in the subapical region co-stained with Mpdz. Immunostaing was also localized in the apical region.
Specimen S2D: postnatal day 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: red - Patj; green - Mpdz (assay MGI:7506785).
Structure Level Pattern Image Note
TS27: neural retina Present Regionally restricted S2D , S2F In the cKO, close to the periphery, immunopositive ectopic cells were found. as well as ectopic immunolabeled cells that co-stained Mpdz.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory