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Gene Expression Data
Assay Details
Assay
Reference: J:60642 Gradwohl G, et al., neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1607-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7705879
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1e: embryonic day 10.5 (more )
Note: Double labeled: blue - Gcg; brown - Neurog3 (assay MGI:7705870).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1e
Specimen 1f: embryonic day 15.5 (more )
Note: Double labeled: brown - Gcg and Ins1 (assay MGI:7705881) and Ins2 (assay MGI:7708883); blue - Neurog3 (assay MGI:7705870).
Structure Level Pattern Image Note
TS23: endocrine pancreas Present 1f
Specimen 3c: postnatal newborn (more )
Structure Cell Type Level Pattern Image Note
TS27: endocrine pancreas pancreatic A cell Present 3c
Specimen 3c': postnatal newborn; Neurog3tm1Fgu/Neurog3tm1Fgu (more )
Structure Cell Type Level Pattern Image Note
TS27: endocrine pancreas pancreatic endocrine cell Absent 3c' No hormone-containing cells detected in mutant.
Specimen 3h: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present 3h Expression detected as early as E9.5.
Specimen 3h': embryonic day 9.5; Neurog3tm1Fgu/Neurog3tm1Fgu (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Absent 3h' No hormone-containing cell detected in mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
MGI 6.24 		The Jackson Laboratory