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Gene Expression Data
Assay Details
Assay
Reference: J:76800 North TE, et al., Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity. 2002 May;16(5):661-72
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7707694
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Ptprc (assay MGI:7707695).
Structure Cell Type Level Pattern Image Note
TS19: aorta-gonad-mesonephros hematopoietic stem cell Present 2A 10x , 2A 60x Expression in Ptprc-expressing hematopoietic stem cells in paraaortic mesenchyme.
TS19: aorta-gonad-mesonephros mesenchymal cell Present 2A 60x , 2A 10x
TS19: aorta-gonad-mesonephros endothelial cell Present Regionally restricted 2A 10x , 2A 60x Expression in endothelial cells that do not express Ptprc.
Specimen 3A left: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A left
Specimen 3A left-middle: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Pecam1 (assay MGI:7707697).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A left-middle
Specimen 3A middle-right: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Kdr (assay MGI:7707698).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A middle-right
Specimen 3A right: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Cdh5 (assay MGI:7707699).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A right
Specimen 4B: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Kit (assay MGI:7707700).
Structure Cell Type Level Pattern Image Note
TS19: aorta-gonad-mesonephros endothelial cell Present 4B Co-expression with Kit in endothelial cells
TS19: aorta-gonad-mesonephros mesenchymal cell Present Regionally restricted 4B Co-expression with Kit n mesenchymal cells directly under the endothelium.
TS19: aorta-gonad-mesonephros hematopoietic stem cell Present Regionally restricted 4B Co-expression with Kit in intraaortic hemaptopoietic clusters.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
MGI 6.24 		The Jackson Laboratory