Mki67 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:321836 Zhao K, et al., LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7711942
Gene symbol:	Mki67
Gene name:	antigen identified by monoclonal antibody Ki 67

Antibody:	Anti-Ki67 (ab15580)
Detection system:	Secondary antibody

Results

1I Ctrl ©

Specimen 1I Ctrl: embryonic day 13.5 (more

)
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7711946).

Structure	Level	Pattern	Image	Note
TS21: heart right ventricle	Present		1I Ctrl

1I cKO ©

Specimen 1I cKO: embryonic day 13.5; Lonp1^tm1.1Zzy/Lonp1^tm1.1Zzy, Tg(Mef2c-cre)2Blk/0 (more

)
Note: Conditional mutant. Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7711946).

Structure	Level	Pattern	Image	Note
TS21: heart right ventricle	Present		1I cKO	Reduced proliferation was primarily in cardiomyocytes.

2H Ctrl ©

2H' ©

Specimen 2 Ctrl H/H': embryonic day 11.5 (more

)
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7711946).

Structure	Level	Pattern	Image	Note
TS19: heart	Present		2H' , 2H Ctrl

2H cKO ©

2H" ©

Specimen 2 cKO H/H": embryonic day 11.5; Lonp1^tm1.1Zzy/Lonp1^tm1.1Zzy, Tg(Tnnt2-cre)5Blh/0 (more

)
Note: Conditional mutant. Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7711946).

Structure	Level	Pattern	Image	Note
TS19: heart	Present		2H cKO , 2H"	Significantly reduced cardiomyocyte proliferation was seen.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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