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Gene Expression Data
Assay Details
Assay
Reference: J:352627 Baltar J, et al., Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn. Neural Dev. 2024 Jul 24;19(1):13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7767883
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti Pax2 Z-RX2 (71-6000)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1Ba2: embryonic day 14.5 (more )
Note: Double labeled: green - Pax2; magenta - Kirrel1 (assay MGI:7767882).
Structure Cell Type Level Pattern Image Note
TS22: spinal cord dorsal horn GABAergic neuron Present Regionally restricted 1Ba2 , 1Ba3 Pax2 is a marker for dILA GABAergic neuronal cell population. Extensive co-localization was observed with Kirrel1.
Specimen 2Ea1: embryonic day 14.5 (more )
Note: Triple labeled: magenta - Pax2; blue - Kirrel1 (assay MGI:7767882); green - Lmx1b (assay MGI:7767884).
Structure Cell Type Level Pattern Image Note
TS22: spinal cord dorsal horn GABAergic neuron Present Regionally restricted 2Ea1 Pax2 is a marker for dILA GABAergic neuronal cell population. Extensive co-localization was observed with Kirrel1.
Specimen 2Eb1: embryonic day 14.5; Drgxtm1And/Drgxtm1And (more )
Note: Triple labeled: magenta - Pax2; blue - Kirrel1 (assay MGI:7767882); green - Lmx1b (assay MGI:7767884).
Structure Cell Type Level Pattern Image Note
TS22: spinal cord dorsal horn GABAergic neuron Present Regionally restricted 2Eb1 Pax2 is a marker for dILA GABAergic neuronal cell population. Less co-localization was observed with Kirrel1 in the mutant compared with wild type.
Specimen 2Ec1: embryonic day 16.5 (more )
Note: Triple labeled: magenta - Pax2; blue - Kirrel1 (assay MGI:7767882); green - Lmx1b (assay MGI:7767884).
Structure Cell Type Level Pattern Image Note
TS24: spinal cord dorsal horn GABAergic neuron Present Regionally restricted 2Ec1 Pax2 is a marker for dILA GABAergic neuronal cell population. Less co-localization was observed with Kirrel1 in the E16.5 dorsal horn.
Specimen 2Ed1: embryonic day 16.5; Drgxtm1And/Drgxtm1And (more )
Note: Triple labeled: magenta - Pax2; blue - Kirrel1 (assay MGI:7767882); green - Lmx1b (assay MGI:7767884).
Structure Cell Type Level Pattern Image Note
TS24: spinal cord dorsal horn GABAergic neuron Present Regionally restricted 2Ed1 Pax2 is a marker for dILA GABAergic neuronal cell population. Similar to the wild type, less co-localization was observed with Kirrel1 in the mutant E16.5 dorsal horn.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory