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Apeh Gene Detail
Summary
  • Symbol
    Apeh
  • Name
    acylpeptide hydrolase
  • Synonyms
    MGC:38101, N-acylaminoacyl peptide hydrolase
  • Feature Type
    protein coding gene
  • IDs
    MGI:88041
    NCBI Gene: 235606
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:107962613-107971736 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.07 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88041
 protein coding gene Chr9:107962612-107971805 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035286
 protein coding gene Chr9:110014469-110023603 (-)
A/J MGP_AJ_G0035265
 protein coding gene Chr9:105990886-105999961 (-)
AKR/J MGP_AKRJ_G0035197
 protein coding gene Chr9:108635708-108644783 (-)
BALB/cJ MGP_BALBcJ_G0035259
 protein coding gene Chr9:105687662-105696737 (-)
C3H/HeJ MGP_C3HHeJ_G0034969
 protein coding gene Chr9:109034173-109043248 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035779
 protein coding gene Chr9:112994394-113003469 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032677
 protein coding gene Chr9:103425611-103434750 (-)
CAST/EiJ MGP_CASTEiJ_G0034280
 protein coding gene Chr9:108990938-109000046 (-)
CBA/J MGP_CBAJ_G0034937
 protein coding gene Chr9:116984253-116993333 (-)
DBA/2J MGP_DBA2J_G0035098
 protein coding gene Chr9:105446310-105455385 (-)
FVB/NJ MGP_FVBNJ_G0035046
 protein coding gene Chr9:104215395-104224470 (-)
LP/J MGP_LPJ_G0035174
 protein coding gene Chr9:110202913-110212047 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035085
 protein coding gene Chr9:118579357-118588487 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035800
 protein coding gene Chr9:108918096-108927225 (-)
PWK/PhJ MGP_PWKPhJ_G0033987
 protein coding gene Chr9:105767701-105776841 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033822
 protein coding gene Chr9:108974444-108984681 (-)
WSB/EiJ MGP_WSBEiJ_G0034401
 protein coding gene Chr9:108793933-108803013 (-)



Homology
more
  • Human Ortholog
    APEH, acylaminoacyl-peptide hydrolase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APEH, acylaminoacyl-peptide hydrolase
  • Synonyms
    AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH
  • Links
    NCBI Gene ID: 327
    neXtProt AC: NX_P13798
    UniProt: P13798

  • Chr Location
    3p21.31; chr3:49673117-49683971 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    2
  • cDNA Data
    118
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 235606 NCBI Gene Model | MGI Sequence Detail 9124 C57BL/6J ±  kb
transcript NM_001410500 RefSeq | MGI Sequence Detail 2408 ZRU/MplStud  
polypeptide Q8R146 UniProt | EBI | MGI Sequence Detail 732 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 121
    Genomic 3
    cDNA 118

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1351
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:11449 Degen SJ, et al., Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development. Biochemistry. 1991 Oct 8;30(40):9781-91
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory