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C1qc Gene Detail
Summary
  • Symbol
    C1qc
  • Name
    complement component 1, q subcomponent, C chain
  • Synonyms
    C1qg
  • Feature Type
    protein coding gene
  • IDs
    MGI:88225
    NCBI Gene: 12262
  • Alliance
    gene page
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:136617115-136620225 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 69.05 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88225
 protein coding gene Chr4:136617115-136620376 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028974
 protein coding gene Chr4:139482777-139486038 (-)
A/J MGP_AJ_G0028933
 protein coding gene Chr4:133547901-133551171 (-)
AKR/J MGP_AKRJ_G0028885
 protein coding gene Chr4:137393235-137396505 (-)
BALB/cJ MGP_BALBcJ_G0028957
 protein coding gene Chr4:134212259-134215529 (-)
C3H/HeJ MGP_C3HHeJ_G0028671
 protein coding gene Chr4:137689525-137692795 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029398
 protein coding gene Chr4:144460778-144464039 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026669
 protein coding gene Chr4:126574576-126577848 (-)
CAST/EiJ MGP_CASTEiJ_G0028103
 protein coding gene Chr4:135839409-135842684 (-)
CBA/J MGP_CBAJ_G0028636
 protein coding gene Chr4:148452682-148455952 (-)
DBA/2J MGP_DBA2J_G0028785
 protein coding gene Chr4:133951435-133954705 (-)
FVB/NJ MGP_FVBNJ_G0028752
 protein coding gene Chr4:132911526-132914796 (-)
LP/J MGP_LPJ_G0028884
 protein coding gene Chr4:139569283-139572544 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028778
 protein coding gene Chr4:152590382-152593652 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029436
 protein coding gene Chr4:137873961-137877222 (-)
PWK/PhJ MGP_PWKPhJ_G0027823
 protein coding gene Chr4:130743997-130747267 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027649
 protein coding gene Chr4:133665630-133668871 (-)
WSB/EiJ MGP_WSBEiJ_G0028181
 protein coding gene Chr4:138031722-138034992 (-)



Homology
more
  • Human Ortholog
    C1QC, complement C1q C chain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C1QC, complement C1q C chain
  • Synonyms
    C1Q-C, C1QD3, C1QG
  • Links
    NCBI Gene ID: 714
    neXtProt AC: NX_P02747
    UniProt: P02747

  • Chr Location
    1p36.12; chr1:22643014-22648110 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    42
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12262 NCBI Gene Model | MGI Sequence Detail 3111 C57BL/6J ±  kb
    transcript NM_001419959 RefSeq | MGI Sequence Detail 1102 ZRU/MplStud  
    polypeptide Q02105 UniProt | EBI | MGI Sequence Detail 246 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 47
      Genomic 3
      cDNA 43
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-1698, MGI:2140252
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 4
      Gene Ontology 11
      Phenotypes 11
    • Earliest
      J:3065 Petry F, et al., Isolation, sequence analysis and characterization of cDNA clones coding for the C chain of mouse C1q. Sequence similarity of complement subcomponent C1q, collagen type VIII and type X and precerebellin. Eur J Biochem. 1992 Oct 1;209(1):129-34
    • Latest
      J:345949 Xu D, et al., Complement in breast milk modifies offspring gut microbiota to promote infant health. Cell. 2024 Feb 1;187(3):750-763.e20
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory