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Cd5 Gene Detail
Summary
  • Symbol
    Cd5
  • Name
    CD5 antigen
  • Synonyms
    Ly-1, Ly-12, Ly-A, Lyt-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88340
    NCBI Gene: 12507
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10695471-10716390 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 7.16 cM
  • Mapping Data
    63 experiments
Strain
Comparison
more
  • SNPs within 2kb
    759 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88340
 protein coding gene Chr19:10694480-10716390 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024856
 protein coding gene Chr19:8077507-8098382 (-)
A/J MGP_AJ_G0024824
 protein coding gene Chr19:7533830-7555099 (-)
AKR/J MGP_AKRJ_G0024799
 protein coding gene Chr19:7827593-7848362 (-)
BALB/cJ MGP_BALBcJ_G0024824
 protein coding gene Chr19:7575415-7596228 (-)
C3H/HeJ MGP_C3HHeJ_G0024590
 protein coding gene Chr19:7724348-7745090 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025272
 protein coding gene Chr19:8434233-8458286 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022699
 protein coding gene Chr19:7953509-7974620 (-)
CAST/EiJ MGP_CASTEiJ_G0024063
 protein coding gene Chr19:7363451-7384181 (-)
CBA/J MGP_CBAJ_G0024564
 protein coding gene Chr19:8479266-8500003 (-)
DBA/2J MGP_DBA2J_G0024691
 protein coding gene Chr19:7539321-7560063 (-)
FVB/NJ MGP_FVBNJ_G0024658
 protein coding gene Chr19:7584257-7604906 (-)
LP/J MGP_LPJ_G0024778
 protein coding gene Chr19:8037699-8058550 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024685
 protein coding gene Chr19:8383339-8405289 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025320
 protein coding gene Chr19:7842323-7863152 (-)
PWK/PhJ MGP_PWKPhJ_G0023808
 protein coding gene Chr19:6984871-7006139 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023613
 protein coding gene Chr19:7023716-7044726 (-)
WSB/EiJ MGP_WSBEiJ_G0024125
 protein coding gene Chr19:7739923-7761664 (-)



Homology
more
  • Human Ortholog
    CD5, CD5 molecule
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD5, CD5 molecule
  • Synonyms
    LEU1, T1
  • Links
    NCBI Gene ID: 921
    neXtProt AC: NX_P06127
    UniProt: P06127

  • Chr Location
    11q12.2; chr11:61093963-61127852 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 3 alleles in 4 genetic backgrounds
    10 phenotypes from multigenic genotypes
    61 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene does not result in a phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    7
  • cDNA Data
    19
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12507 NCBI Gene Model | MGI Sequence Detail 20920 C57BL/6J ±  kb
    transcript NM_007650 RefSeq | MGI Sequence Detail 2069 ZRU/MplStud  
    polypeptide P13379 UniProt | EBI | MGI Sequence Detail 494 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      Genomic 2
      cDNA 19
      Primer pair 1
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-11947, MGD-MRK-11950, MGD-MRK-12073, MGD-MRK-1866
    References
    more
    • Summaries
      All 165
      Developmental Gene Expression 3
      Gene Ontology 14
      Phenotypes 61
    • Earliest
      J:5073 Boyse EA, et al., Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse. Proc R Soc Lond B Biol Sci. 1968 Jun 11;170(19):175-93
    • Latest
      J:357723 Sirbulescu RF, et al., Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis. FASEB J. 2024 Jul 15;38(13):e23796
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory