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Csrp1 Gene Detail
Summary
  • Symbol
    Csrp1
  • Name
    cysteine and glycine-rich protein 1
  • Synonyms
    CRP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88549
    NCBI Gene: 13007
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135647799-135679970 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.23 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1100 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88549
 protein coding gene Chr1:135614650-135679970 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016526
 protein coding gene Chr1:139498646-139535055 (+)
A/J MGP_AJ_G0016509
 protein coding gene Chr1:134225578-134256390 (+)
AKR/J MGP_AKRJ_G0016474
 protein coding gene Chr1:138213665-138248859 (+)
BALB/cJ MGP_BALBcJ_G0016469
 protein coding gene Chr1:134544195-134576749 (+)
C3H/HeJ MGP_C3HHeJ_G0016295
 protein coding gene Chr1:138318280-138349301 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016930
 protein coding gene Chr1:144529821-144564524 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014641
 protein coding gene Chr1:127326096-127359180 (+)
CAST/EiJ MGP_CASTEiJ_G0015875
 protein coding gene Chr1:137399650-137432709 (+)
CBA/J MGP_CBAJ_G0016268
 protein coding gene Chr1:149535837-149567658 (+)
DBA/2J MGP_DBA2J_G0016374
 protein coding gene Chr1:133218332-133250244 (+)
FVB/NJ MGP_FVBNJ_G0016373
 protein coding gene Chr1:131863384-131895280 (+)
LP/J MGP_LPJ_G0016445
 protein coding gene Chr1:140735606-140768975 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016398
 protein coding gene Chr1:155187222-155220164 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016966
 protein coding gene Chr1:137986790-138019705 (+)
PWK/PhJ MGP_PWKPhJ_G0015661
 protein coding gene Chr1:132254249-132287034 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015448
 protein coding gene Chr1:136963942-137001003 (+)
WSB/EiJ MGP_WSBEiJ_G0015938
 protein coding gene Chr1:138020074-138053794 (+)



Homology
more
  • Human Ortholog
    CSRP1, cysteine and glycine rich protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSRP1, cysteine and glycine rich protein 1
  • Synonyms
    CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286
  • Links
    NCBI Gene ID: 1465
    neXtProt AC: NX_P21291
    UniProt: P21291

  • Chr Location
    1q32.1; chr1:201483530-201509456 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased neointima formation following wire-induced arterial injury.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1144
  • Tissues
    279
  • cDNA Data
    368
  • Literature Summary
    15
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026421 Ensembl Gene Model | MGI Sequence Detail 32172 C57BL/6J ±  kb
transcript ENSMUST00000097561 Ensembl | MGI Sequence Detail 1828 Not Applicable  
polypeptide ENSMUSP00000095169 Ensembl | MGI Sequence Detail 193 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005958 cysteine and glycine-rich protein 1
    (term hierarchy)
  • InterPro Domains
    IPR001781 Zinc finger, LIM-type
  • GlyGen
    P97315 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
Molecular
Reagents
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  • All nucleic 376
    cDNA 371
    Primer pair 4
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-2207, MGI:1353622, MGI:2138134, MGI:2138600
References
more
  • Summaries
    All 63
    Developmental Gene Expression 15
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory