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Egfbp2 Gene Detail
Summary
  • Symbol
    Egfbp2
  • Name
    epidermal growth factor binding protein type B
  • Synonyms
    Egfbp-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:95292
    NCBI Gene: 13647
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
Homology
more
  • Human Ortholog
    KLK1, kallikrein 1
  • Vertebrate Orthologs
    12
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLK1, kallikrein 1
  • Synonyms
    hK1, Klk6, KLKR
  • Links
    NCBI Gene ID: 3816
    neXtProt AC: NX_P06870
    UniProt: P06870

  • Chr Location
    19q13.33; chr19:50819146-50823787 (-)  GRCh38
  • Human Ortholog
    KLK2, kallikrein related peptidase 2
  • Synonyms
    hGK-1, hK2, KLK2A2
  • Links
    NCBI Gene ID: 3817
    neXtProt AC: NX_P20151
    UniProt: P20151

  • Chr Location
    19q13.33; chr19:50861568-50880567 (+)  GRCh38
Human Diseases
more
  • Diseases
    5 with human KLK1 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    3
  • Other Mouse Links
    GEO
Sequences &
Gene Models
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  • All Sequences
    8
  • RefSeq
    2
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic AH001901 GenBank | ENA | DDBJ | MGI Sequence Detail 3003 Not Specified ±  kb
transcript NM_010115 RefSeq | MGI Sequence Detail 858 ICR  
polypeptide P36368 UniProt | EBI | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 87
    Genomic 82
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-9317, MGD-MRK-9320
References
more
  • Summaries
    All 23
    Gene Ontology 7
  • Earliest
    J:7072 Mason AJ, et al., Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature. 1983 May 26;303(5915):300-7
  • Latest
    J:96866 Takada K, et al., Autoimmunity against a tissue kallikrein in IQI/Jic Mice: a model for Sjogren's syndrome. J Biol Chem. 2005 Feb 4;280(5):3982-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory