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f Gene Detail
Summary
  • Symbol
    f
  • Name
    flexed-tail
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:95473
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 13, Syntenic
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • RFLP
    4
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    28 phenotypes from 1 allele in 3 genetic backgrounds
    6 phenotypes from multigenic genotypes
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutants for the spontaneous recessive flexed-tail allele have axial skeletal abnormalities, abnormal heme biosynthesis, and a transient sideroblastic anemia that disappears a few weeks after birth. The tail and belly spot phenotypes have variable penetrance.
Molecular
Reagents
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  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 28
    Phenotypes 26
  • Earliest
    J:12951 Hunt HR, et al., Flexed Tail in the Mouse, Mus Musculus. Genetics. 1933 Jul;18(4):335-66
  • Latest
    J:151008 Lenox LE, et al., Extramedullary erythropoiesis in the adult liver requires BMP-4/Smad5-dependent signaling. Exp Hematol. 2009 May;37(5):549-58
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory