Human Disease | Mouse Models | ||||
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IDs
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IDs
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IDs
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early conceptus |
embryo ectoderm |
embryo endoderm |
embryo mesoderm |
embryo mesenchyme |
extraembryonic component |
alimentary system |
auditory system |
branchial arches |
cardiovascular system |
connective tissue |
endocrine system |
exocrine system |
hemolymphoid system |
integumental system |
limbs |
liver and biliary system |
musculoskeletal system |
nervous system |
olfactory system |
reproductive system |
respiratory system |
urinary system |
visual system |
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Transcription Start Site | Location | Distance from Gene 5'-end |
Tssr12148 | Chr1:71692321-71692340 (-) | 28 bp |
Tssr12147 | Chr1:71691335-71691338 (-) | 1,022 bp |
Tssr12146 | Chr1:71689749-71689775 (-) | 2,597 bp |
Tssr12145 | Chr1:71688448-71688472 (-) | 3,899 bp |
Tssr12144 | Chr1:71687242-71687264 (-) | 5,106 bp |
Tssr12143 | Chr1:71682235-71682285 (-) | 10,099 bp |
Tssr12142 | Chr1:71681239-71681265 (-) | 11,107 bp |
Tssr12141 | Chr1:71681181-71681197 (-) | 11,170 bp |
Tssr12140 | Chr1:71680430-71680473 (-) | 11,907 bp |
Tssr12139 | Chr1:71679563-71679577 (-) | 12,789 bp |
Tssr12138 | Chr1:71677696-71677748 (-) | 14,637 bp |
Tssr12137 | Chr1:71677664-71677686 (-) | 14,684 bp |
Tssr12136 | Chr1:71676494-71676505 (-) | 15,859 bp |
Tssr12135 | Chr1:71676438-71676449 (-) | 15,915 bp |
Tssr12134 | Chr1:71671264-71671304 (-) | 21,075 bp |
Tssr12133 | Chr1:71671235-71671254 (-) | 21,114 bp |
Tssr12132 | Chr1:71668543-71668575 (-) | 23,800 bp |
Tssr12131 | Chr1:71667629-71667650 (-) | 24,719 bp |
Tssr12130 | Chr1:71667598-71667611 (-) | 24,754 bp |
Tssr12129 | Chr1:71667260-71667289 (-) | 25,084 bp |
Tssr12128 | Chr1:71666506-71666521 (-) | 25,845 bp |
Tssr12127 | Chr1:71666438-71666492 (-) | 25,894 bp |
Tssr12126 | Chr1:71665389-71665410 (-) | 26,959 bp |
Tssr12125 | Chr1:71665198-71665223 (-) | 27,148 bp |
Tssr12124 | Chr1:71663303-71663319 (-) | 29,048 bp |
Tssr12123 | Chr1:71658636-71658656 (-) | 33,713 bp |
Tssr12122 | Chr1:71657784-71657797 (-) | 34,568 bp |
Tssr12121 | Chr1:71651716-71651764 (-) | 40,619 bp |
Tssr12120 | Chr1:71651660-71651684 (-) | 40,687 bp |
Tssr12119 | Chr1:71648662-71648707 (-) | 43,674 bp |
Tssr12118 | Chr1:71647137-71647160 (-) | 45,210 bp |
Tssr12117 | Chr1:71646016-71646032 (-) | 46,335 bp |
Tssr12116 | Chr1:71645975-71646009 (-) | 46,367 bp |
Tssr12115 | Chr1:71645942-71645960 (-) | 46,408 bp |
Tssr12114 | Chr1:71645123-71645145 (-) | 47,225 bp |
Tssr12113 | Chr1:71643000-71643012 (-) | 49,353 bp |
Tssr12112 | Chr1:71641540-71641561 (-) | 50,808 bp |
Tssr12111 | Chr1:71640401-71640453 (-) | 51,932 bp |
Tssr12110 | Chr1:71639574-71639616 (-) | 52,764 bp |
Tssr12109 | Chr1:71639496-71639526 (-) | 52,848 bp |
Tssr12108 | Chr1:71636596-71636610 (-) | 55,756 bp |
Tssr12107 | Chr1:71634883-71634913 (-) | 57,461 bp |
Tssr12106 | Chr1:71632297-71632318 (-) | 60,051 bp |
Tssr12105 | Chr1:71632280-71632296 (-) | 60,071 bp |
Tssr12104 | Chr1:71629971-71629998 (-) | 62,374 bp |
Tssr12103 | Chr1:71626085-71626105 (-) | 66,264 bp |
Tssr12102 | Chr1:71625383-71625392 (-) | 66,971 bp |
Tssr12101 | Chr1:71624717-71624749 (-) | 67,626 bp |
QTL | Genetic Location* | Genome Location (GRCm39) | Reference | QTL Note |
Insq2 | Chr1, syntenic | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. | |
Insq6 | Chr1, 38.01 cM | Chr1:73726922-73727077 | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. |
Nidd6 | Chr1, 65.11 cM | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. | |
Obq2 | Chr1, 6.50 cM | Chr1:20941620-20941887 | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. |
Obq7 | Chr1, 33.31 cM | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. | |
Obq9 | Chr1, 74.68 cM | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. | |
Wt6q1 | Chr1, syntenic | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. | |
Wt6q2 | Chr1, syntenic | J:99477 | Authors used novel data mining tool ExQuest to identify novel candidate genes for existing diabesity QTLs. Next, candidate gene expression in the liver, adipose, and pancreas of diabesity-prone Tally Ho mice and diabesity-resistant C57BL/6J mice was assessed by quantitative PCR analysis. Several potential candidate genes, some with no previous association to diabesity QTLs, were identified. Since QTL intervals may be large and could contain hundreds or thousands of potential candidate genes, this method allows researchers to focus on those with strong potential as well as identify novel candidate genes. A potential candidate gene for Obq2 at 15 cM on mouse Chromosome 1 as identified by ExQuest is Gsta3. For QTLs Obq7 (28.7 cM), Wt6q1 (27 cM), Insq2 (36cM), and Insq6 (37 cM), potential candidate genes Aox1 (23.2 cM), Fn1 (36.1 cM), Pecr, Igfbp2 (36.1 cM), Plcd4 (39.2 cM), Scg2 (43.6 cM), Irs1, and Inpp5d (57 cM) were identified. For QTL Nidd6 (77 cM), potential candidate gene Qscn6 was identified. For QTL Obq9 (88.4 cM), potential candidate genes Fmo1, Fmo3, and Apoa2 (92.6 cM) were identified. For QTL Wt6q2 (108 cM), potential candidate gene Hsd11b1 was identified. |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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