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Gda Gene Detail
Summary
  • Symbol
    Gda
  • Name
    guanine deaminase
  • Feature Type
    protein coding gene
  • IDs
    MGI:95678
    NCBI Gene: 14544
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:21368671-21450025 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 14.32 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3018 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95678
 protein coding gene Chr19:21368671-21450809 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024977
 protein coding gene Chr19:19420955-19504117 (-)
A/J MGP_AJ_G0024954
 protein coding gene Chr19:18373653-18454772 (-)
AKR/J MGP_AKRJ_G0024924
 protein coding gene Chr19:19065735-19149847 (-)
BALB/cJ MGP_BALBcJ_G0024953
 protein coding gene Chr19:18369795-18450632 (-)
C3H/HeJ MGP_C3HHeJ_G0024711
 protein coding gene Chr19:19020837-19104109 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025395
 protein coding gene Chr19:20093118-20177179 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022814
 protein coding gene Chr19:18596597-18678090 (-)
CAST/EiJ MGP_CASTEiJ_G0024179
 protein coding gene Chr19:18698138-18779584 (-)
CBA/J MGP_CBAJ_G0024689
 protein coding gene Chr19:20906675-20999913 (-)
DBA/2J MGP_DBA2J_G0024821
 protein coding gene Chr19:18379294-18460135 (-)
FVB/NJ MGP_FVBNJ_G0024782
 protein coding gene Chr19:18232999-18316703 (-)
LP/J MGP_LPJ_G0024905
 protein coding gene Chr19:19396158-19476520 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024809
 protein coding gene Chr19:21039214-21127759 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025450
 protein coding gene Chr19:19010370-19095076 (-)
PWK/PhJ MGP_PWKPhJ_G0023928
 protein coding gene Chr19:17914216-18005523 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023733
 protein coding gene Chr19:18278685-18364814 (-)
WSB/EiJ MGP_WSBEiJ_G0024247
 protein coding gene Chr19:19089808-19173600 (-)



Homology
more
  • Human Ortholog
    GDA, guanine deaminase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GDA, guanine deaminase
  • Synonyms
    CYPIN, GAH, GUANASE, NEDASIN
  • Links
    NCBI Gene ID: 9615
    neXtProt AC: NX_Q9Y2T3
    UniProt: Q9Y2T3

  • Chr Location
    9q21.13; chr9:72114595-72259869 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    830
  • Tissues
    104
  • cDNA Data
    59
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14544 NCBI Gene Model | MGI Sequence Detail 81355 C57BL/6J ±  kb
    transcript NM_010266 RefSeq | MGI Sequence Detail 5417 ZRU/MplStud  
    polypeptide Q9R111 UniProt | EBI | MGI Sequence Detail 454 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 61
      cDNA 61

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-10024, MGI:2147637, MGI:2147689
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 5
    • Earliest
      J:7470 Bonhomme F, et al., Biochemical diversity and evolution in the genus Mus. Biochem Genet. 1984 Apr;22(3-4):275-303
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory