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H2-T18 Gene Detail
Summary
  • Symbol
    H2-T18
  • Name
    histocompatibility 2, T region locus 18
  • Synonyms
    H-2T18, Tla, TL Ag
  • Feature Type
    unclassified gene
  • IDs
    MGI:95950
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 17, Syntenic
  • Mapping Data
    19 experiments
Strain
Comparison
more
  • RFLP
    7
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from multigenic genotypes
    28 phenotype references
This locus contains the coding member of a gene pair encoding the thymic leukemia antigen or TL antigen in "d haplotype" mice such as BALB/c. The other member of this gene pair, H2-T3d, is a pseudogene.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    2
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
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  • All Sequences
    5
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
transcript AK153910 GenBank | ENA | DDBJ | MGI Sequence Detail 2105 NOD  
polypeptide Q3U531 UniProt | EBI | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050208 Antigen-presenting and immune regulatory MHC class I-related
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
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  • All nucleic 25
    Genomic 19
    cDNA 3
    Other 3

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-10433, MGD-MRK-10546, MGD-MRK-15131
References
more
  • Summaries
    All 75
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 28
  • Earliest
    J:13118 BOYSE EA, et al., GENETIC DETERMINATION OF THE TL (THYMUSLEUKAEMIA) ANTIGEN IN THE MOUSE. Nature. 1964 Feb 22;201:779
  • Latest
    J:349914 Beaver M, et al., C1q is elevated during chronic Staphylococcus epidermidis central nervous system catheter infection. Front Immunol. 2024;15:1342467
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory