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H2ac18 Gene Detail
Summary
  • Symbol
    H2ac18
  • Name
    H2A clustered histone 18
  • Synonyms
    H2a-615, Hist2, Hist2h2aa1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96097
    NCBI Gene: 15267
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:96152813-96153398 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.69 cM, cytoband F1-F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    68 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96097
 protein coding gene Chr3:96152813-96153439 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027571
 protein coding gene Chr3:94000608-94001193 (-)
AKR/J MGP_AKRJ_G0027538
 protein coding gene Chr3:96212368-96212939 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0025372
 protein coding gene Chr3:90324058-90326041 (-)
CAST/EiJ MGP_CASTEiJ_G0026766
 protein coding gene Chr3:95812350-95812935 (+)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027432
 protein coding gene Chr3:93304828-93305990 (-)
FVB/NJ MGP_FVBNJ_G0027403
 protein coding gene Chr3:91367516-91368101 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0026496
 protein coding gene Chr3:93198132-93199227 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026317
 protein coding gene Chr3:94140719-94141304 (-)
WSB/EiJ MGP_WSBEiJ_G0026849
 protein coding gene Chr3:96236068-96238067 (-)



Homology
more
  • Human Ortholog
    H2AC18, H2A clustered histone 18
  • Vertebrate Orthologs
    31
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2AC18, H2A clustered histone 18
  • Synonyms
    H2A, H2A.2, H2a-615, H2AC19, H2AFO, H2A/O, H2A/q, HIST2H2AA, HIST2H2AA3
  • Links
    NCBI Gene ID: 8337
    neXtProt AC: NX_Q6FI13
    UniProt: Q6FI13

  • Chr Location
    1q21.2; chr1:149842218-149842750 (-)  GRCh38
  • Human Ortholog
    H2AC19, H2A clustered histone 19
  • Synonyms
    H2AC18, H2A/R, HIST2H2AA4
  • Links
    NCBI Gene ID: 723790
    neXtProt AC: NX_Q6FI13
    UniProt: Q6FI13

  • Chr Location
    1q21.2; chr1:149851061-149851594 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    2
  • cDNA Data
    8
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064220 Ensembl Gene Model | MGI Sequence Detail 586 C57BL/6J ±  kb
transcript ENSMUST00000078756 Ensembl | MGI Sequence Detail 586 Not Applicable  
polypeptide ENSMUSP00000077814 Ensembl | MGI Sequence Detail 130 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • GlyGen
    Q6GSS7 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 15
    Genomic 4
    cDNA 10
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-10729, MGI:2139710, MGI:6325014
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:7225 Sittman DB, et al., Structure of a cluster of mouse histone genes. Nucleic Acids Res. 1983 Oct 11;11(19):6679-97
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory