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Lx Gene Detail
Summary
  • Symbol
    Lx
  • Name
    luxate
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:96856
    NCBI Gene: 17034
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 5, Syntenic
  • Mapping Data
    7 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutant homozygotes exhibit preaxial polydactyly or oligodactyly of the hindfeet, reductions in the tibia, femur and pubis, fewer sacral vertebrae, and defects of the urogenital system. Heterozygotes may have preaxial polydactyly of the hindfeet.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-11946
References
more
  • Summaries
    All 15
    Phenotypes 8
  • Earliest
    J:222 CARTER TC, Position of luxate in the third linkage group of the house mouse. Nature. 1949 Dec 31;164(4183):1138
  • Latest
    J:81331 Yada Y, et al., The mouse polydactylous mutation, luxate (lx), causes anterior shift of the anteroposterior border in the developing hindlimb bud. Int J Dev Biol. 2002;46(7):975-82
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory