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Ly6c1 Gene Detail
Summary
  • Symbol
    Ly6c1
  • Name
    lymphocyte antigen 6 family member C1
  • Synonyms
    Ly6c, Ly-6C
  • Feature Type
    protein coding gene
  • IDs
    MGI:96882
    NCBI Gene: 17067
  • Member of
    Ly6 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:74915867-74920679 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.29 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    13
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96882
 protein coding gene Chr15:74915867-74920690 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0021907
 protein coding gene Chr15:72512681-72516557 (+)
AKR/J MGP_AKRJ_G0021891
 protein coding gene Chr15:74413520-74417277 (+)
BALB/cJ MGP_BALBcJ_G0021916
 protein coding gene Chr15:72472409-72476172 (+)
C3H/HeJ MGP_C3HHeJ_G0021690
 protein coding gene Chr15:74508686-74512690 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0021209
 protein coding gene Chr15:75492160-75492700 (-)
CBA/J MGP_CBAJ_G0021655
 protein coding gene Chr15:80543281-80547047 (+)
DBA/2J MGP_DBA2J_G0021780
 protein coding gene Chr15:72068994-72072811 (+)
FVB/NJ MGP_FVBNJ_G0021761
 protein coding gene Chr15:71081385-71085163 (+)
LP/J MGP_LPJ_G0021853
 protein coding gene Chr15:75443572-75443801 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021785
 protein coding gene Chr15:85839008-85842962 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022374
 protein coding gene Chr15:74356160-74555699 (-)
PWK/PhJ MGP_PWKPhJ_G0020950
 protein coding gene Chr15:72131435-72131776 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Ly6c1
  • Find Mice (IMSR)
    14 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    8
  • cDNA Data
    112
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079018 Ensembl Gene Model | MGI Sequence Detail 4813 C57BL/6J ±  kb
transcript ENSMUST00000188845 Ensembl | MGI Sequence Detail 784 Not Applicable  
polypeptide ENSMUSP00000139559 Ensembl | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 116
    Genomic 4
    cDNA 112

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12005, MGD-MRK-12048, MGI:2145928, MGI:2145929
References
more
  • Summaries
    All 85
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 3
    Phenotypes 24
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:335303 Shay TF, et al., Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Sci Adv. 2023 Apr 21;9(16):eadg6618
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory