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Rhox5 Gene Detail
Summary
  • Symbol
    Rhox5
  • Name
    reproductive homeobox 5
  • Synonyms
    Pem
  • Feature Type
    protein coding gene
  • IDs
    MGI:97538
    NCBI Gene: 18617
  • Member of
    Rhox cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:36891657-36897305 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, Syntenic
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97538
protein coding gene ChrX:36891636-36897311 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035650
protein coding gene ChrX:32731972-32736006 (+)
A/J MGP_AJ_G0035637
protein coding gene ChrX:32790030-32794824 (+)
AKR/J MGP_AKRJ_G0035555
protein coding gene ChrX:33534593-33538627 (+)
BALB/cJ MGP_BALBcJ_G0035621
protein coding gene ChrX:32485763-32489797 (+)
C3H/HeJ MGP_C3HHeJ_G0035326
protein coding gene ChrX:33043920-33047954 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036151
protein coding gene ChrX:33453933-33457967 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033004
protein coding gene ChrX:31180338-31184362 (+)
CAST/EiJ MGP_CASTEiJ_G0034616
protein coding gene ChrX:21073511-21077544 (+)
CBA/J MGP_CBAJ_G0035301
protein coding gene ChrX:34268600-34272634 (+)
DBA/2J MGP_DBA2J_G0035453
protein coding gene ChrX:32615097-32619131 (+)
FVB/NJ MGP_FVBNJ_G0035403
protein coding gene ChrX:32354693-32358727 (+)
LP/J MGP_LPJ_G0035542
protein coding gene ChrX:33097356-33101390 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035440
protein coding gene ChrX:34651459-34655493 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036170
protein coding gene ChrX:32742881-32746915 (+)
PWK/PhJ MGP_PWKPhJ_G0034319
protein coding gene ChrX:20668154-20672163 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034164
protein coding gene ChrX:21601139-21605152 (+)
WSB/EiJ MGP_WSBEiJ_G0034763
protein coding gene ChrX:32453793-32457815 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18617 NCBI Gene Model | MGI Sequence Detail 5649 C57BL/6J ±  kb
transcript NM_008818 RefSeq | MGI Sequence Detail 869 ZRU/MplStud  
polypeptide P52651 UniProt | EBI | MGI Sequence Detail 210 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 56
    Primer pair 7
    Other 4

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-13228, MGI:2147823
References
more
  • Summaries
    All 94
    Developmental Gene Expression 53
    Gene Ontology 13
    Phenotypes 10
  • Earliest
    J:10765 Wilkinson MF, et al., A novel oncofetal gene is expressed in a stage-specific manner in murine embryonic development [published erratum appears in Dev Biol 1991 Jul;146(1):263]. Dev Biol. 1990 Oct;141(2):451-5
  • Latest
    J:342643 Oh Y, et al., Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice. Biol Reprod. 2023 Oct 13;109(4):520-532

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory