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Bpifa2 Gene Detail
Summary
  • Symbol
    Bpifa2
  • Name
    BPI fold containing family A, member 2
  • Synonyms
    Bpifa2e, Psp
  • Feature Type
    protein coding gene
  • IDs
    MGI:97787
    NCBI Gene: 19194
  • Alliance
    gene page
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153850196-153857993 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 76.15 cM
  • Mapping Data
    33 experiments
Strain
Comparison
more
  • SNPs within 2kb
    288 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97787
 protein coding gene Chr2:153850185-153857999 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026705
 protein coding gene Chr2:158719186-158726992 (+)
A/J MGP_AJ_G0026671
 protein coding gene Chr2:152330631-152338443 (+)
AKR/J MGP_AKRJ_G0026642
 protein coding gene Chr2:156813710-156821524 (+)
BALB/cJ MGP_BALBcJ_G0026681
 protein coding gene Chr2:152669443-152677199 (+)
C3H/HeJ MGP_C3HHeJ_G0026423
 protein coding gene Chr2:157184661-157192472 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027130
 protein coding gene Chr2:163342727-163350541 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024500
 protein coding gene Chr2:145903559-145911353 (+)
CAST/EiJ MGP_CASTEiJ_G0025884
 protein coding gene Chr2:157449767-157457586 (+)
CBA/J MGP_CBAJ_G0026402
 protein coding gene Chr2:169343105-169350916 (+)
DBA/2J MGP_DBA2J_G0026537
 protein coding gene Chr2:151557827-151565639 (+)
FVB/NJ MGP_FVBNJ_G0026503
 protein coding gene Chr2:150004711-150012527 (+)
LP/J MGP_LPJ_G0026642
 protein coding gene Chr2:158836127-158843933 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026525
 protein coding gene Chr2:173326090-173333902 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027185
 protein coding gene Chr2:156699236-156707050 (+)
PWK/PhJ MGP_PWKPhJ_G0025618
 protein coding gene Chr2:151090870-151098697 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025421
 protein coding gene Chr2:155560712-155569349 (+)
WSB/EiJ MGP_WSBEiJ_G0025954
 protein coding gene Chr2:157609144-157616948 (+)



Homology
more
  • Human Ortholog
    BPIFA2, BPI fold containing family A member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BPIFA2, BPI fold containing family A member 2
  • Synonyms
    bA49G10.1, C20orf70, PSP, SPLUNC2
  • Links
    NCBI Gene ID: 140683
    neXtProt AC: NX_Q96DR5
    UniProt: Q96DR5

  • Chr Location
    20q11.21; chr20:33161768-33181412 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    762
  • Tissues
    35
  • cDNA Data
    2086
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19194 NCBI Gene Model | MGI Sequence Detail 7798 C57BL/6J ±  kb
    transcript NM_008953 RefSeq | MGI Sequence Detail 974 FVB/N  
    polypeptide P07743 UniProt | EBI | MGI Sequence Detail 235 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000015548 BPI fold-containing family A member 2
      (term hierarchy)
    • InterPro Domains
      IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
      IPR052507 BPI fold-containing antibacterial protein
      IPR017942 Lipid-binding serum glycoprotein, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 2095
      Genomic 6
      cDNA 2086
      Primer pair 1
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13651
    References
    more
    • Summaries
      All 66
      Developmental Gene Expression 5
      Gene Ontology 7
      Phenotypes 7
    • Earliest
      J:13365 Owerbach D, et al., Genetic determination of a parotid secretory protein in mouse. Hereditas. 1978;89:146 (Abstr.)
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory