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Sult2a1 Gene Detail
Summary
  • Symbol
    Sult2a1
  • Name
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
  • Synonyms
    mSTa1, Std, Sth1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98430
    NCBI Gene: 20859
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:13530171-13571334 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 8.02 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    924 from dbSNP Build 142
  • Strain Annotations
    14
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98430
 protein coding gene Chr7:13530171-13571335 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031677
 protein coding gene Chr7:11018054-11075029 (+)
A/J MGP_AJ_G0031651
 protein coding gene Chr7:11165598-11244663 (-)
AKR/J MGP_AKRJ_G0031573
 protein coding gene Chr7:11638508-11715197 (-)
BALB/cJ MGP_BALBcJ_G0031656
 protein coding gene Chr7:11303714-11394023 (-)
C3H/HeJ MGP_C3HHeJ_G0031379
 protein coding gene Chr7:11848649-11894429 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032121
 protein coding gene Chr7:11644894-11727564 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031336
 protein coding gene Chr7:12040878-12118164 (-)
DBA/2J MGP_DBA2J_G0031493
 protein coding gene Chr7:11038309-11145314 (-)
FVB/NJ MGP_FVBNJ_G0031449
 protein coding gene Chr7:10737420-10789517 (+)
LP/J MGP_LPJ_G0031580
 protein coding gene Chr7:11637019-11698178 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031484
 protein coding gene Chr7:12316875-12446771 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032151
 protein coding gene Chr7:10889885-10948039 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030831
 protein coding gene Chr7:11427517-11450571 (-)



Homology
more
  • Human Ortholog
    SULT2A1, sulfotransferase family 2A member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SULT2A1, sulfotransferase family 2A member 1
  • Synonyms
    DHEAS, DHEA-ST, DHEA-ST8, HST, hSTa, ST2, ST2A1, ST2A3, STD, SULT2A3
  • Links
    NCBI Gene ID: 6822
    neXtProt AC: NX_Q06520
    UniProt: Q06520

  • Chr Location
    19q13.33; chr19:47870467-47886315 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SULT2A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    30
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078798 Ensembl Gene Model | MGI Sequence Detail 41164 C57BL/6J ±  kb
transcript ENSMUST00000108522 Ensembl | MGI Sequence Detail 1020 Not Applicable  
polypeptide ENSMUSP00000104162 Ensembl | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    2.8.2.14, 2.8.2.2
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR000863 Sulfotransferase domain
  • GlyGen
    P52843 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    cDNA 8
    Primer pair 3
    Other 1
Other
Accession IDs
less
MGD-MRK-14618, MGD-MRK-36122, MGI:107551
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:26013 Leiter EH, et al., The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. V. Interaction between the db gene and hepatic sex steroid sulfotransferases correlates with gender-dependent susceptibility to hyperglycemia. Endocrinology. 1989 Feb;124(2):912-22
  • Latest
    J:277278 Butali A, et al., Genomic analyses in African populations identify novel risk loci for cleft palate. Hum Mol Genet. 2019 Mar 15;28(6):1038-1051
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory